Evidence map›Paper›PMID 26840627›Full record

ArticleClinical cardiology2016

Depression and Multiple Rehospitalizations in Patients With Heart Failure.

Kenneth E Freedland, Robert M Carney, Michael W Rich, Brian C Steinmeyer, Judith A Skala, Victor G Dávila-Román

Open access · greenAbstract read
In one paragraph

Article in Clinical cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 70 citations in OpenAlex.

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  19. Functional support and burden among out-of-home supporters of heart failure patients with and without depression.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kenneth E FreedlandDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Robert M CarneyDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Michael W RichDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Brian C SteinmeyerDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Judith A SkalaPalliative Care Department, Veterans Administration Medical Center, St. Louis, Missouri.
Victor G Dávila-RománDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Washington University in St. Louis · USUnited States Department of Veterans Affairs · US

Funding

DEPRESSION AND REHOSPITALIZATION IN PATIENTS WITH HEART FAILURER01HL119286 · NHLBI · WASHINGTON UNIVERSITY · PI FREEDLAND, KENNETH E · 2014 to 2018
$3.5M
DEPRESSION AND HEART FAILURE IN THE ELDERLYR01MH051419 · NIMH · WASHINGTON UNIVERSITY · PI FREEDLAND, KENNETH E · 1993 to 1999
–
NHLBI NIH HHS R01 HL119286NIMH NIH HHS R01 MH051419
6 · The paper itself

Abstract

backgroundThere have been few studies of the effect of depression on rehospitalization in patients with heart failure (HF), and even fewer on its role in multiple rehospitalizations. HYPOTHESIS: Depression is an independent risk factor for multiple readmissions in patients with HF.

methodsA cohort of 662 patients with HF who were discharged alive after hospitalization were interviewed to evaluate symptoms of depression and were followed for 1 year. All-cause readmissions were documented by chart review. A marginal proportional rates model was used to model the effect of depression on the rate of rehospitalization with adjustment for known predictors of HF outcomes.

resultsDepression symptoms predicted multiple readmissions (adjusted hazard ratio [HR]: 1.08, 95% confidence interval [CI]: 1.03-1.13, P = 0.0008). Compared with patients without depression, those who met the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria for major depression at index were at the highest risk for multiple rehospitalizations (HR: 1.51, 95% CI: 1.15-1.97, P = 0.003).

conclusionsDepression is an independent risk factor for multiple all-cause readmissions in patients with HF.

Indexed as

Patient ReadmissionAdultAgedDepressionFemaleHeart FailureHumansLinear ModelsMaleMiddle AgedOdds RatioPrognosisProportional Hazards ModelsPsychiatric Status Rating ScalesRisk AssessmentRisk Factors

Identifiers

PMID26840627
PMCPMC4879082
OpenAlexW2415756364

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.