Evidence map›Paper›PMID 26840570›Full record

ArticleJournal of viral hepatitis2016

Public health clinic-based hepatitis C testing and linkage to care in Baltimore.

O Falade-Nwulia, S H Mehta, J Lasola, C Latkin, A Niculescu, C O'Connor, P Chaulk, K Ghanem, K R Page, M S Sulkowski and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of viral hepatitis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Trial
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  8. Article
  9. Article
  10. Review
  11. Article
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  14. Reply to MacDonald et al.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Hepatitis C Screening: Barriers to Linkage to Care.Journal of clinical and translational hepatology · 2019
    Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

O Falade-NwuliaJohns Hopkins University School of Medicine, Baltimore, MD, USA.
S H MehtaJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
J LasolaJohns Hopkins University School of Medicine, Baltimore, MD, USA.
C LatkinJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
A NiculescuJohns Hopkins University School of Medicine, Baltimore, MD, USA.
C O'ConnorJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
P ChaulkBaltimore City Health Department, Baltimore, MD, USA.
K GhanemJohns Hopkins University School of Medicine, Baltimore, MD, USA.
K R PageJohns Hopkins University School of Medicine, Baltimore, MD, USA.
M S SulkowskiJohns Hopkins University School of Medicine, Baltimore, MD, USA.
D L ThomasJohns Hopkins University School of Medicine, Baltimore, MD, USA.

Funding

Management/Hepatitis C/HIV-infected and Uninfected IDU'sR01DA016065 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SULKOWSKI, MARK SEBASTIAN · 2003 to 2018
$8.0M
HIV HCV Coinfection Antiviral Therapy and FibrosisR37DA013806 · NIDA · JOHNS HOPKINS UNIVERSITY · PI THOMAS, DAVID L · 2010 to 2019
$7.0M
Patient Oriented Research in Hepatitis C-infected Injection Drug UsersK24DA034621 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SULKOWSKI, MARK SEBASTIAN · 2012 to 2022
$1.2M
NIDA NIH HHS K24 DA034621NIDA NIH HHS R01 DA016065NIDA NIH HHS R37 DA013806PHS HHS R37013806
6 · The paper itself

Abstract

Testing and linkage to care are important determinants of hepatitis C virus (HCV) treatment effectiveness. Public health clinics serve populations at high risk of HCV. We investigated their potential to serve as sites for HCV testing, initiation of and linkage to HCV care. Cross-sectional study of patients accessing sexually transmitted infection (STI) care at the Baltimore City Health Department (BCHD) STI clinics, from June 2013 through April 2014 was conducted. Logistic regression was used to assess factors associated with HCV infection and specialist linkage to care. Between 24 June 2013 and 15 April 2014, 2681 patients were screened for HCV infection. Overall, 189 (7%) were anti-HCV positive, of whom 185 (98%) received follow-up HCV RNA testing, with 155 (84%) testing RNA positive. Of 155 RNA-positive individuals, 138 (89%) returned to the STI clinic for HCV RNA results and initial HCV care including counselling regarding transmission and harm reduction in alcohol, and 132 (85%) were referred to a specialist for HCV care. With provision of patient navigation services, 81 (52%) attended an offsite HCV specialist appointment. Alcohol use and lack of insurance coverage were associated with lower rates of specialist linkage (OR 0.4 [95% CI 0.1-0.9] and OR 0.4 [95% CI 0.1-0.9], respectively). We identified a high prevalence of HCV infection in BCHD STI clinics. With availability of patient navigation services, a large proportion of HCV-infected patients linked to off-site specialist care.

Indexed as

AdultBaltimoreCross-Sectional StudiesFemaleHepatitis CHumansMaleMass ScreeningPublic Health AdministrationYoung Adulthazardous alcohol consumptionHCV treatmentImplementation sciencerapid testingsexually transmitted infections clinic

Identifiers

PMID26840570
PMCPMC4836954

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.