Evidence map›Paper›PMID 26839809›Full record

ArticleScientia pharmaceutica

Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities.

Niels Guldbrandsen, Maria De Mieri, Mahabir Gupta, Eleni Liakou, Harris Pratsinis, Dimitris Kletsas, Eliza Chaita, Nektarios Aligiannis, Alexios-Leandros Skaltsounis, Matthias Hamburger

Open access · goldAbstract read
In one paragraph

Article in Scientia pharmaceutica. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Niels GuldbrandsenDivision of Pharmaceutical Biology, University of Basel, Klingelbergstrasse 40, CH-4056 Basel, Switzerland.
Maria De MieriDivision of Pharmaceutical Biology, University of Basel, Klingelbergstrasse 40, CH-4056 Basel, Switzerland.
Mahabir GuptaCIFLORPAN, College of Pharmacy, University of Panama, Apartado 0824-00172, Panama, Republic of Panama.
Eleni LiakouLaboratory of Cell Proliferation & Ageing, Institute of Biosciences & Applications, NCSR "Demokritos", 15310, Athens, Greece.
Harris PratsinisLaboratory of Cell Proliferation & Ageing, Institute of Biosciences & Applications, NCSR "Demokritos", 15310, Athens, Greece.
Dimitris KletsasLaboratory of Cell Proliferation & Ageing, Institute of Biosciences & Applications, NCSR "Demokritos", 15310, Athens, Greece.
Eliza ChaitaKorres S.A. Natural Products, 57th Athens-Lamia National Road, 32011, Inofyta, Greece; Department of Pharmacognosy & Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Zografou, 15771, Greece.
Nektarios AligiannisDepartment of Pharmacognosy & Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Zografou, 15771, Greece.
Alexios-Leandros SkaltsounisDepartment of Pharmacognosy & Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Zografou, 15771, Greece.
Matthias HamburgerDivision of Pharmaceutical Biology, University of Basel, Klingelbergstrasse 40, CH-4056 Basel, Switzerland.
University of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A library of 600 taxonomically diverse Panamanian plant extracts was screened for DPPH scavenging and UV-B protective activities, and the methanolic extracts of Mosquitoxylum jamaicense, Combretum cacoucia, and Casearia commersionia were submitted to HPLC-based activity profiling. The compounds located in the active time windows were isolated and identified as gallic acid derivatives and flavonoids. Gallic acid methyl ester (3) and digallic acid derivatives (2, 6) showed the highest DPPH scavenging activity (<10 μg/mL), while protocatechuic acid (7) and isoquercitrin (10) exhibited the highest UV-B protective properties.

Indexed as

DPPH scavengingHPLC-based activity profilingPanamanian plant extractUV-B protection

Identifiers

PMID26839809
PMCPMC4727770
OpenAlexW2323361822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.