Evidence map›Paper›PMID 26839661›Full record

ArticleWorld journal of cardiology2016

Percutaneous assist devices in acute myocardial infarction with cardiogenic shock: Review, meta-analysis.

Francesco Romeo, Maria Cristina Acconcia, Domenico Sergi, Alessia Romeo, Simona Francioni, Flavia Chiarotti, Quintilio Caretta

Open access · bronzeAbstract read
In one paragraph

Article in World journal of cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Predictors of short-term mortality in cardiogenic shock: insights from an Egyptian multicenter registry.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Francesco RomeoFrancesco Romeo, Domenico Sergi, Alessia Romeo, Department of Cardiovascular Disease, University of Rome - Tor Vergata, 00133 Rome, Italy.
Maria Cristina AcconciaFrancesco Romeo, Domenico Sergi, Alessia Romeo, Department of Cardiovascular Disease, University of Rome - Tor Vergata, 00133 Rome, Italy.
Domenico SergiFrancesco Romeo, Domenico Sergi, Alessia Romeo, Department of Cardiovascular Disease, University of Rome - Tor Vergata, 00133 Rome, Italy.
Alessia RomeoFrancesco Romeo, Domenico Sergi, Alessia Romeo, Department of Cardiovascular Disease, University of Rome - Tor Vergata, 00133 Rome, Italy.
Simona FrancioniFrancesco Romeo, Domenico Sergi, Alessia Romeo, Department of Cardiovascular Disease, University of Rome - Tor Vergata, 00133 Rome, Italy.
Flavia ChiarottiFrancesco Romeo, Domenico Sergi, Alessia Romeo, Department of Cardiovascular Disease, University of Rome - Tor Vergata, 00133 Rome, Italy.
Quintilio CarettaFrancesco Romeo, Domenico Sergi, Alessia Romeo, Department of Cardiovascular Disease, University of Rome - Tor Vergata, 00133 Rome, Italy.
University of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the impact of percutaneous cardiac support in cardiogenic shock (CS) complicating acute myocardial infarction (AMI), treated with percutaneous coronary intervention.

methodsWe selected all of the studies published from January 1(st), 1997 to May 15(st), 2015 that compared the following percutaneous mechanical support in patients with CS due to AMI undergoing myocardial revascularization: (1) intra-aortic balloon pump (IABP) vs Medical therapy; (2) percutaneous left ventricular assist devices (PLVADs) vs IABP; (3) complete extracorporeal life support with extracorporeal membrane oxygenation (ECMO) plus IABP vs IABP alone; and (4) ECMO plus IABP vs ECMO alone, in patients with AMI and CS undergoing myocardial revascularization. We evaluated the impact of the support devices on primary and secondary endpoints. Primary endpoint was the inhospital mortality due to any cause during the same hospital stay and secondary endpoint late mortality at 6-12 mo of follow-up.

resultsOne thousand two hundred and seventy-two studies met the initial screening criteria. After detailed review, only 30 were selected. There were 6 eligible randomized controlled trials and 24 eligible observational studies totaling 15799 patients. We found that the inhospital mortality was: (1) significantly higher with IABP support vs medical therapy (RR = +15%, P = 0.0002); (2) was higher, although not significantly, with PLVADs compared to IABP (RR = +14%, P = 0.21); and (3) significantly lower in patients treated with ECMO plus IABP vs IABP (RR = -44%, P = 0.0008) or ECMO (RR = -20%, P = 0.006) alone. In addition, Trial Sequential Analysis showed that in the comparison of IABP vs medical therapy, the sample size was adequate to demonstrate a significant increase in risk due to IABP.

conclusionInhospital mortality was significantly higher with IABP vs medical therapy. PLVADs did not reduce early mortality. ECMO plus IABP significantly reduced inhospital mortality compared to IABP.

Indexed as

Cardiogenic shockExtracorporeal membrane oxygenationImpellaIntra-aortic balloon pumpMeta-analysisTandemHeart

Identifiers

PMID26839661
PMCPMC4728111
OpenAlexW2274562798

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.