Evidence map›Paper›PMID 26839651›Full record

ArticleWorld journal of gastrointestinal endoscopy2016

Evidence to suggest adoption of water exchange deserves broader consideration: Its pain alleviating impact occurs in 90% of investigators.

Sergio Cadoni, Mauro Liggi, Premysl Falt, Stefano Sanna, Mariangela Argiolas, Viviana Fanari, Paolo Gallittu, Donatella Mura, Maria L Porcedda, Vit Smajstrla and 2 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Sergio CadoniSergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Digestive Endoscopy Unit, St. Barbara Hospital, 09016 Iglesias, Italy.
Mauro LiggiSergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Digestive Endoscopy Unit, St. Barbara Hospital, 09016 Iglesias, Italy.
Premysl FaltSergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Digestive Endoscopy Unit, St. Barbara Hospital, 09016 Iglesias, Italy.
Stefano SannaSergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Digestive Endoscopy Unit, St. Barbara Hospital, 09016 Iglesias, Italy.
Mariangela ArgiolasSergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Digestive Endoscopy Unit, St. Barbara Hospital, 09016 Iglesias, Italy.
Viviana FanariSergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Digestive Endoscopy Unit, St. Barbara Hospital, 09016 Iglesias, Italy.
Paolo GallittuSergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Digestive Endoscopy Unit, St. Barbara Hospital, 09016 Iglesias, Italy.
Donatella MuraSergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Digestive Endoscopy Unit, St. Barbara Hospital, 09016 Iglesias, Italy.
Maria L PorceddaSergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Digestive Endoscopy Unit, St. Barbara Hospital, 09016 Iglesias, Italy.
Vit SmajstrlaSergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Digestive Endoscopy Unit, St. Barbara Hospital, 09016 Iglesias, Italy.
Matteo ErriuSergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Digestive Endoscopy Unit, St. Barbara Hospital, 09016 Iglesias, Italy.
Felix W LeungSergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Digestive Endoscopy Unit, St. Barbara Hospital, 09016 Iglesias, Italy.
Ospedale San Paolo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine whether observations were reproducible among investigators.

methodsFrom March 2013 through June 2014, 18-85-year-old diagnostic and 50-70-year-old screening patients were enrolled at each center to on-demand sedation colonoscopy with water exchange (WE), water immersion (WI) and insufflation with air or CO2 for insertion and withdrawal [air or carbon dioxide (AICD)]. Data were aggregated for analysis. PRIMARY OUTCOME: Variations in real-time maximum insertion pain (0 = none, 1-2 = discomfort, 10 = worst).

resultsOne thousand and ninety-one cases analyzed: WE (n = 371); WI (n = 338); AICD (n = 382). Demographics and indications were comparable. The WE group had the lowest real-time maximum insertion pain score, mean (95%CI): WE 2.8 (2.6-3.0), WI 3.8 (3.5-4.1) and AICD 4.4 (4.1-4.7), P < 0.0005. Ninety percent of the colonoscopists were able to use water exchange to significantly decrease maximum insertion pain scores. One investigator had high insertion pain in all groups, nonetheless WE achieved the lowest real-time maximum insertion pain score. WE had the highest proportions of patients with painless unsedated colonoscopy (vs WI, P = 0.013; vs AICD, P < 0.0005); unsedated colonoscopy with only minor discomfort (vs AICD, P < 0.0005), and completion without sedation (vs AICD, P < 0.0005).

conclusionAggregate data confirm superiority of WE in lowering colonoscopy real-time maximum insertion pain and need for sedation. Ninety percent of investigators were able to use water exchange to significantly decrease maximum insertion pain scores. Our results suggest that the technique deserves consideration in a broader scale.

Indexed as

ColonoscopyColonoscopy painPainless colonoscopyWater exchangeWater immersion

Identifiers

PMID26839651
PMCPMC4724028
OpenAlexW2401304255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.