Evidence map›Paper›PMID 26839575›Full record

ArticleEmerging themes in epidemiology2016

Hypertension and diabetes in Africa: design and implementation of a large population-based study of burden and risk factors in rural and urban Malawi.

Amelia Catharine Crampin, Ndoliwe Kayuni, Alemayehu Amberbir, Crispin Musicha, Olivier Koole, Terence Tafatatha, Keith Branson, Jacqueline Saul, Elenaus Mwaiyeghele, Lawrence Nkhwazi and 6 more

Open access · goldAbstract read
In one paragraph

Article in Emerging themes in epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
10.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
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  7. Characterizing the evolving SARS-CoV-2 seroprevalence in urban and rural Malawi between February 2021 and April 2022: A population-based cohort study.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Amelia Catharine CrampinKaronga Prevention Study, Karonga, Malawi ; London School of Hygiene and Tropical Medicine, London, UK.
Ndoliwe KayuniKaronga Prevention Study, Karonga, Malawi.
Alemayehu AmberbirKaronga Prevention Study, Karonga, Malawi ; London School of Hygiene and Tropical Medicine, London, UK.
Crispin MusichaKaronga Prevention Study, Karonga, Malawi.
Olivier KooleKaronga Prevention Study, Karonga, Malawi ; London School of Hygiene and Tropical Medicine, London, UK.
Terence TafatathaKaronga Prevention Study, Karonga, Malawi.
Keith BransonLondon School of Hygiene and Tropical Medicine, London, UK.
Jacqueline SaulLondon School of Hygiene and Tropical Medicine, London, UK.
Elenaus MwaiyegheleKaronga Prevention Study, Karonga, Malawi.
Lawrence NkhwaziKaronga Prevention Study, Karonga, Malawi.
Amos PhiriKaronga Prevention Study, Karonga, Malawi.
Alison Jane PriceKaronga Prevention Study, Karonga, Malawi ; London School of Hygiene and Tropical Medicine, London, UK.
Beatrice MwagombaMalawi Ministry of Health, Lilongwe, Malawi.
Charles MwansamboMalawi Ministry of Health, Lilongwe, Malawi.
Shabbar JaffarLondon School of Hygiene and Tropical Medicine, London, UK.
Moffat Joha NyirendaKaronga Prevention Study, Karonga, Malawi ; London School of Hygiene and Tropical Medicine, London, UK.
Malawi Epidemiology and Intervention Research Unit · MWLondon School of Hygiene & Tropical Medicine · GBMinistry of Health · MW

Funding

Wellcome Trust 098610
6 · The paper itself

Abstract

backgroundThe emerging burden of cardiovascular disease and diabetes in sub-Saharan Africa threatens the gains made in health by the major international effort to combat infectious diseases. There are few data on distribution of risk factors and outcomes in the region to inform an effective public health response. A comprehensive research programme is being developed aimed at accurately documenting the burden and drivers of NCDs in urban and rural Malawi; to design and test intervention strategies. The programme includes population surveys of all people aged 18 years and above, linking individuals with newly diagnosed hypertension and diabetes to healthcare and supporting clinical services. The successes, challenges and lessons learnt from the programme to date are discussed.

resultsOver 20,000 adults have been recruited in rural Karonga and urban Lilongwe. The urban population is significantly younger and wealthier than the rural population. Employed urban individuals, particularly males, give particular recruitment challenges; male participation rates were 80.3 % in the rural population and 43.6 % in urban, whilst female rates were 93.6 and 75.6 %, respectively. The study is generating high quality data on hypertension, diabetes, lipid abnormalities and risk factors.

conclusionsIt is feasible to develop large scale studies that can reliably inform the public health approach to diabetes, cardiovascular disease and other NCDs in Sub-Saharan Africa. It is essential for studies to capture both rural and urban populations to address disparities in risk factors, including age structure. Innovative approaches are needed to address the specific challenge of recruiting employed urban males.

Indexed as

DiabetesEpidemiologyHypertensionMethodsNon-communicable diseasesSub-Saharan Africa

Identifiers

PMID26839575
PMCPMC4736489
OpenAlexW2305797390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.