ReviewNature nanotechnology2016
Decoding DNA, RNA and peptides with quantum tunnelling.
Review in Nature nanotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed.
- Chiral discrimination of amino acids in meteorite and desert soil extracts via single-molecule nanogap conductance.Nature communications · 2026Article
- Electrical discrimination of lysine methylation states at the single-molecule level.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026Article
- Fingerprint Recognition Based on Molecular-Scale Conductance Response via Electrochemically Gated Quantum Tunnelling.Sensors (Basel, Switzerland) · 2026Article
- From Artificial Intelligence to Quantum Computing: Promise and Prudence in the Field of Cardiovascular Medicine.Journal of the American Heart Association · 2026Article
- Decoding information stored in DNAs through single-molecule electrical detection platforms.Innovation (Cambridge (Mass.)) · 2025Review
- Current Approaches in Genome Assembly of Human Fungal Pathogens.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Integration of Artificial Intelligence and Quantum Transport toward Stereoselective Identification of Carbohydrate Isomers.ACS central science · 2024Article
- Electromigrated Gold Nanogap Tunnel Junction Arrays: Fabrication and Electrical Behavior in Liquid and Gaseous Media.ACS applied materials & interfaces · 2024Article
- Total variation denoising-based method of identifying the states of single molecules in break junction data.Discover nano · 2024Article
- Fabrication of electron tunneling probes for measuring single-protein conductance.Nature protocols · 2023Review
- Direct biomolecule discrimination in mixed samples using nanogap-based single-molecule electrical measurement.Scientific reports · 2023Article
- Advances in single-molecule junctions as tools for chemical and biochemical analysis.Nature chemistry · 2023Review
- Highly efficient and robust π-FISH rainbow for multiplexed in situ detection of diverse biomolecules.Nature communications · 2023Article
- Electronic analysis of hydrogen-bonded molecular complexes: the case of DNA sensed in a functionalized nanogap.RSC advances · 2023Article
- Functionalized electrodes embedded in nanopores: read-out enhancement?Chemistry, an Asian journal · 2023Review
- Ab Initio Properties of Hybrid Cove-Edged Graphene Nanoribbons as Metallic Electrodes for Peptide Sequencing via Transverse Tunneling Current.ACS omega · 2022Article
- Measuring conductance switching in single proteins using quantum tunneling.Science advances · 2022Article
- Protein Sequencing, One Molecule at a Time.Annual review of biophysics · 2022Review
- Direct observation of DNA alterations induced by a DNA disruptor.Scientific reports · 2022Article
- Scalable Fabrication of Metallic Nanogaps at the Sub-10 nm Level.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drugs and treatments could be precisely tailored to an individual patient by extracting their cellular- and molecular-level information. For this approach to be feasible on a global scale, however, information on complete genomes (DNA), transcriptomes (RNA) and proteomes (all proteins) needs to be obtained quickly and at low cost. Quantum mechanical phenomena could potentially be of value here, because the biological information needs to be decoded at an atomic level and quantum tunnelling has recently been shown to be able to differentiate single nucleobases and amino acids in short sequences. Here, we review the different approaches to using quantum tunnelling for sequencing, highlighting the theoretical background to the method and the experimental capabilities demonstrated to date. We also explore the potential advantages of the approach and the technical challenges that must be addressed to deliver practical quantum sequencing devices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.