ArticlePlant physiology2016
PUB1 Interacts with the Receptor Kinase DMI2 and Negatively Regulates Rhizobial and Arbuscular Mycorrhizal Symbioses through Its Ubiquitination Activity in Medicago truncatula.
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Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed.
- Review
- Crosstalk and reciprocal regulation of phosphorylation and ubiquitination mediated by receptor-like kinases and U-box E3 ligases during plant growth and environmental stress responses.Plant communications · 2026Review
- Ubiquitination as a multi-layer regulatory network in legume-rhizobium symbiosis.Plant cell reports · 2026Review
- A LjBAK1-associated E3 ubiquitin ligase, LjPUB7, negatively regulates early symbiosis by targeting NFRs.BMC plant biology · 2025Article
- Article
- Differential Responses ofPlants (Basel, Switzerland) · 2023Article
- Review
- Comparative transcriptome analysis of molecular mechanisms underlying adventitious root developments in Huangshan Bitter tea (Frontiers in plant science · 2023Article
- Roles of a CCR4-NOT complex component GmNOT4-1 in regulating soybean nodulation.Frontiers in plant science · 2023Article
- Emerging roles of the ubiquitin-proteasome pathway in enhancing crop yield by optimizing seed agronomic traits.Plant cell reports · 2022Review
- Physiological and transcriptomic response of Medicago truncatula to colonization by high- or low-benefit arbuscular mycorrhizal fungi.Mycorrhiza · 2022Article
- Receptor-Like Kinases Sustain Symbiotic Scrutiny.Plant physiology · 2020Review
- TheFrontiers in plant science · 2020Article
- Celebrating 20 Years of Genetic Discoveries in Legume Nodulation and Symbiotic Nitrogen Fixation.The Plant cell · 2020Review
- A lysin motif effector subverts chitin-triggered immunity to facilitate arbuscular mycorrhizal symbiosis.The New phytologist · 2020Article
- A combination of chitooligosaccharide and lipochitooligosaccharide recognition promotes arbuscular mycorrhizal associations in Medicago truncatula.Nature communications · 2019Article
- A Lotus japonicus E3 ligase interacts with the Nod Factor Receptor 5 and positively regulates nodulation.BMC plant biology · 2018Article
- The MtDMI2-MtPUB2 Negative Feedback Loop Plays a Role in Nodulation Homeostasis.Plant physiology · 2018Article
- Article
- Plant Signaling and Metabolic Pathways Enabling Arbuscular Mycorrhizal Symbiosis.The Plant cell · 2017Review
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Authors and funding
13 authors.
Tatiana VerniéInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.).ORCID 0000-0003-1387-6370
Sylvie CamutInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.).
Céline CampsInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.).
Céline RembliereInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.).
Fernanda de Carvalho-NiebelInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.).
Malick MbengueInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.).ORCID 0000-0002-7723-7757
Ton TimmersInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.).
Virginie GasciolliInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.).
Richard ThompsonInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.).
Christine le SignorInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.).ORCID 0000-0002-3204-3537
Benoit LefebvreInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.).
Julie CullimoreInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.).
Christine HervéInstitut National de la Recherche Agronomique, Laboratoire des Interactions Plantes-Microorganismes, UMR441, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); Centre National de la Recherche Scientifique, Laboratoire des Interactions Plantes-Microorganismes, UMR2594, Castanet-Tolosan F-31326, France (T.V., S.C., C.C, C.R., F.D.C.-N., M.M., T.T., V.G., B.L., J.C., C.H.); and Institut National de la Recherche Agronomique-UMR1347-Agroecologie AgroSup/Institut National de la Recherche Agronomique/uB, Pôle Génétique & Ecophysiologie GEAPSI, 21065 Dijon France (R.T., C.L.) christine.herve@toulouse.inra.fr.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PUB1, an E3 ubiquitin ligase, which interacts with and is phosphorylated by the LYK3 symbiotic receptor kinase, negatively regulates rhizobial infection and nodulation during the nitrogen-fixing root nodule symbiosis in Medicago truncatula In this study, we show that PUB1 also interacts with and is phosphorylated by DOES NOT MAKE INFECTIONS 2, the key symbiotic receptor kinase of the common symbiosis signaling pathway, required for both the rhizobial and the arbuscular mycorrhizal (AM) endosymbioses. We also show here that PUB1 expression is activated during successive stages of root colonization by Rhizophagus irregularis that is compatible with its interaction with DOES NOT MAKE INFECTIONS 2. Through characterization of a mutant, pub1-1, affected by the E3 ubiquitin ligase activity of PUB1, we have shown that the ubiquitination activity of PUB1 is required to negatively modulate successive stages of infection and development of rhizobial and AM symbioses. In conclusion, PUB1 represents, to our knowledge, a novel common component of symbiotic signaling integrating signal perception through interaction with and phosphorylation by two key symbiotic receptor kinases, and downstream signaling via its ubiquitination activity to fine-tune both rhizobial and AM root endosymbioses.
Indexed as
SymbiosisUbiquitinationColony Count, MicrobialGlomeromycotaMedicago truncatulaMycorrhizaePhosphorylationPlant ProteinsProtein DomainsRhizobiumSaccharomyces cerevisiaeUbiquitin-Protein LigasesPlant ProteinsUbiquitin-Protein Ligases
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