ArticleThe British journal of radiology2016
Prospective evaluation of free-breathing diffusion-weighted imaging for the detection of inflammatory bowel disease with MR enterography in childhood population.
Article in The British journal of radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Diagnostic performance of magnetic resonance enterography and ultrasound in children with inflammatory bowel diseases: a diagnostic test accuracy meta-analysis.European radiology · 2022Pooled it
- Pooled it
- Motion Mitigation Techniques for Abdominal and Cardiac MR Imaging.Journal of magnetic resonance imaging : JMRI · 2026Review
- Imaging of Ulcerative Colitis: The Role of Diffusion-Weighted Magnetic Resonance Imaging.Journal of clinical medicine · 2024Review
- 18F-FDG-PET and other imaging modalities in the diagnosis and management of inflammatory bowel disease.American journal of nuclear medicine and molecular imaging · 2024Review
- Role of abbreviated non-contrast-enhanced MR-enterography in the evaluation of Crohn's disease activity and complications as an alternative for full protocol contrast-enhanced study: A systematic review and meta-analysis.Research in diagnostic and interventional imaging · 2023Article
- Challenges and Strategies to Optimising the Quality of Small Bowel Magnetic Resonance Imaging in Crohn's Disease.Diagnostics (Basel, Switzerland) · 2022Review
- Quantitative assessment of terminal ileum motility on MR enterography in Crohn disease: a feasibility study in children.European radiology · 2021Article
- The value of magnetic resonance enterography in diagnostic difficulties associated with Crohn's disease.Polish journal of radiology · 2021Article
- Comparison between Diffusion-Weighted Sequences with Selective and Non-Selective Fat Suppression in the Evaluation of Crohn's Disease Activity: Are They Equally Useful?Diagnostics (Basel, Switzerland) · 2020Article
- Detection of Crohn's disease with diffusion images versus contrast-enhanced images in pediatric using MR enterography with histopathological correlation.La Radiologia medica · 2019Article
- The Influence of Bowel Preparation on ADC Measurements: Comparison between Conventional DWI and DWIBS Sequences.Medicina (Kaunas, Lithuania) · 2019Observational
- Up-to-date overview of imaging techniques in the diagnosis and management of inflammatory bowel diseases.Przeglad gastroenterologiczny · 2019Review
- Can diffusion weighting replace gadolinium enhancement in magnetic resonance enterography for inflammatory bowel disease in children?Pediatric radiology · 2018Article
- Colonic inflammation in pediatric inflammatory bowel disease: detection with magnetic resonance enterography.Pediatric radiology · 2017Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate prospectively the performance of diffusion-weighted imaging (DWI) for the detection of active lesions on MR enterography (MRE) in children with inflammatory bowel disease (IBD).
methodsMRE of 48 children (mean age 13 years) with suspected or known IBD were blindly analysed by 2 independent readers for the presence of active lesions. Two sets of imaging including DWI and gadolinium-enhanced imaging (GEI) were reviewed. A reader consensus was obtained. The gold standard was histopathological findings. In patient-level analysis and segment-level analysis, sensitivity and specificity were calculated for DWI and GEI and compared using McNemar's test or logistic random-effects models.
resultsAt least 1 active lesion was confirmed in 42 (87.5%) children. Sensitivity and specificity for the detection of at least one lesion were 88.1% (95% CI, 74.3-96.1) and 83.3% (95% CI, 35.9-99.6), respectively, for DWI and 66.7% (95% CI, 50.4-80.4) and 83.3% (95% CI, 35.9-99.6), respectively, for GEI. In segment-level analysis, sensitivity and specificity for the detection of specific segment lesions were 62.5% (95% CI, 48.1-75) and 97.1% (95% CI, 93.5-98.7), respectively, for DWI and 45.7% (95% CI, 30.8-61.3) and 98.2% (95% CI, 95.3-99.4), respectively, for GEI. The sensitivity of DWI was significantly better than that of GEI per patient (p = 0.004) and per segment (p = 0.028).
conclusionDWI demonstrates better performance than GEI for the detection of active lesions in children with IBD. ADVANCES IN KNOWLEDGE: Examination with no intravenous injection-DWI can replace T1 weighted images when paediatric patients are screened with MRE for IBD. Examination performed in free breathing is better tolerated by children.
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