Evidence map›Paper›PMID 26838516›Full record

ArticleNanoscale2016

Nanoparticle-mediated photothermal effect enables a new method for quantitative biochemical analysis using a thermometer.

Guanglei Fu, Sharma T Sanjay, Maowei Dou, XiuJun Li

Abstract read
In one paragraph

Article in Nanoscale, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guanglei FuDepartment of Chemistry, University of Texas at El Paso, 500 West University Ave, El Paso, Texas 79968, USA. xli4@utep.edu.
Sharma T SanjayDepartment of Chemistry, University of Texas at El Paso, 500 West University Ave, El Paso, Texas 79968, USA. xli4@utep.edu.
Maowei DouDepartment of Chemistry, University of Texas at El Paso, 500 West University Ave, El Paso, Texas 79968, USA. xli4@utep.edu.
XiuJun LiDepartment of Chemistry, University of Texas at El Paso, 500 West University Ave, El Paso, Texas 79968, USA. xli4@utep.edu and Biomedical Engineering, University of Texas at El Paso, 500 West University Ave, El Paso, Texas 79968, USA and Border Biomedical Research Center, University of Texas at El Paso, 500 West University Ave, El Paso, Texas 79968, USA.

Funding

Grafting DNA Codes on Paper for Rapid, Low-Cost, and Sensitive Meningitis DiagnosSC2GM105584 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI LI, XIUJUN · 2013 to 2015
$438k
Design of Point of Care Device for the Rapid Diagnosis of PertussisR21AI107415 · NIAID · UNIVERSITY OF TEXAS EL PASO · PI DOMINGUEZ, DELFINA C, LI, XIUJUN · 2015 to 2016
$405k
NIAID NIH HHS R21 AI107415NIAID NIH HHS R21AI107415NIGMS NIH HHS SC2 GM105584NIGMS NIH HHS SC2GM105584
6 · The paper itself

Abstract

A new biomolecular quantitation method, nanoparticle-mediated photothermal bioassay, using a common thermometer as the signal reader was developed. Using an immunoassay as a proof of concept, iron oxide nanoparticles (NPs) captured in the sandwich-type assay system were transformed into a near-infrared (NIR) laser-driven photothermal agent, Prussian blue (PB) NPs, which acted as a photothermal probe to convert the assay signal into heat through the photothermal effect, thus allowing sensitive biomolecular quantitation using a thermometer. This is the first report of biomolecular quantitation using a thermometer and also serves as the first attempt to introduce the nanoparticle-mediated photothermal effect for bioassays.

Indexed as

Biological AssayCalibrationFerric CompoundsFerrocyanidesHot TemperatureHumansImmunoassayMaleMetal NanoparticlesMicroscopy, Electron, TransmissionNanotechnologyProstate-Specific AntigenSpectroscopy, Near-InfraredThermometersFerric Compoundsferric ferrocyanideferric oxideFerrocyanidesProstate-Specific Antigen

Identifiers

PMID26838516
PMCPMC5106188

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.