ArticleCell adhesion & migration2016
Modeling cell shape and dynamics on micropatterns.
Article in Cell adhesion & migration, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- The Floor-Ceiling-Chip, or 2 × 2D = Pseudo-3D-Approaching 3D Cell Morphology and Organization between Two Opposing 2D Substrates with Cell-Adhesive Protein Micropatterns.Advanced healthcare materials · 2026Article
- Migration and proliferation drive the emergence of patterns in co-cultures of differentiating vascular progenitor cells.Mathematical biosciences and engineering : MBE · 2024Article
- Extracellular Cues Govern Shape and Cytoskeletal Organization in Giant Unilamellar Lipid Vesicles.ACS synthetic biology · 2023Article
- Article
- Geometric Control of Cell Behavior by Biomolecule Nanodistribution.ACS biomaterials science & engineering · 2022Article
- Not just a number: What cells feel depends on how they grab it.Biophysical journal · 2022Article
- Sticking around: Cell adhesion patterning for energy minimization and substrate mechanosensing.Biophysical journal · 2022Article
- Subcellular Dynamic Immunopatterning of Cytosolic Protein Complexes on Microstructured Polymer Substrates.ACS sensors · 2021Article
- High-Throughput Methods in the Discovery and Study of Biomaterials and Materiobiology.Chemical reviews · 2021Review
- Mechanotransduction and Stiffness-Sensing: Mechanisms and Opportunities to Control Multiple Molecular Aspects of Cell Phenotype as a Design Cornerstone of Cell-Instructive Biomaterials for Articular Cartilage Repair.International journal of molecular sciences · 2020Review
- The Research Advance of Cell BridgesFrontiers in bioengineering and biotechnology · 2020Review
- Sub-Micropillar Spacing Modulates the Spatial Arrangement of Mouse MC3T3-E1 Osteoblastic Cells.Nanomaterials (Basel, Switzerland) · 2019Article
- Extracellular Matrix Geometry and Initial Adhesive Position Determine Stress Fiber Network Organization during Cell Spreading.Cell reports · 2019Article
- Hydrogel Scaffolds: Towards Restitution of Ischemic Stroke-Injured Brain.Translational stroke research · 2019Review
- Profiling cellular morphodynamics by spatiotemporal spectrum decomposition.PLoS computational biology · 2018Article
- Cellular Response to Surface Morphology: Electrospinning and Computational Modeling.Frontiers in bioengineering and biotechnology · 2018Review
- Physical models of collective cell motility: from cell to tissue.Journal of physics D: Applied physics · 2017Article
- Ring-Shaped Microlanes and Chemical Barriers as a Platform for Probing Single-Cell Migration.Scientific reports · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adhesive micropatterns have become a standard tool to study cells under defined conditions. Applications range from controlling the differentiation and fate of single cells to guiding the collective migration of cell sheets. In long-term experiments, single cell normalization is challenged by cell division. For all of these setups, mathematical models predicting cell shape and dynamics can guide pattern design. Here we review recent advances in predicting and explaining cell shape, traction forces and dynamics on micropatterns. Starting with contour models as the simplest approach to explain concave cell shapes, we move on to network and continuum descriptions as examples for static models. To describe dynamic processes, cellular Potts, vertex and phase field models can be used. Different types of model are appropriate to address different biological questions and together, they provide a versatile tool box to predict cell behavior on micropatterns.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.