ArticleBiomedical microdevices2016
Characterizing tissue stiffness at the tip of a rigid needle using an opto-mechanical force sensor.
Article in Biomedical microdevices, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 36 citations in OpenAlex.
- Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets.Signal transduction and targeted therapy · 2023Review
- Miniaturized optical fiber probe for prostate cancer screening.Biomedical optics express · 2021Article
- Indentation probe with optical fibre array-based optical coherence tomography for material deformation.Journal of microscopy · 2021Article
- In vivo characterization of chick embryo mesoderm by optical coherence tomography-assisted microindentation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
- The Effect of Matrix Stiffness on Human Hepatocyte Migration and Function-An In Vitro Research.Polymers · 2020Article
- A salt-based method to adapt stiffness and biodegradability of porous collagen scaffolds.RSC advances · 2019Article
- Micro-Cantilever Displacement Detection Based in Optical Fiber Tip.Sensors (Basel, Switzerland) · 2019Article
- Effect of substrate stiffness on hepatocyte migration and cellular Young's modulus.Journal of cellular physiology · 2018Article
- Regional variations in stiffness in live mouse brain tissue determined by depth-controlled indentation mapping.Scientific reports · 2018Article
- Stiffening of the nucleus pulposus upon axial loading of the intervertebral disc: An experimental in situ study.JOR spine · 2018Article
- A Portable Stiffness Measurement System.Sensors (Basel, Switzerland) · 2017Article
- Minimally Invasive Micro-Indentation: mapping tissue mechanics at the tip of an 18G needle.Scientific reports · 2017Article
- Fiber Optic Force Sensors for MRI-Guided Interventions and Rehabilitation: A Review.IEEE sensors journal · 2017Article
- Fiber-Optic Fabry-Pérot Interferometers for Axial Force Sensing on the Tip of a Needle.Sensors (Basel, Switzerland) · 2016Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present a novel device that allows the user to measure the Young Modulus of a material at the opening of a 5 mm diameter needle. The device relies on a miniaturized cantilever spring mounted at the end of the needle and interrogated via Fabry-Pérot optical fiber interferometry. The probe is repetitively brought in and out of contact with the sample at the end of the needle by means of a steel cable that is controlled via a piezoelectric actuator located at the proximal end. We demonstrate the ability of our device to detect and quantify layers of varying stiffness during needle insertion in a gelatin phantom and to successfully locate tissue boundaries in bovine liver tissue embedded in gelatin.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.