Evidence map›Paper›PMID 26837840›Full record

ArticleScientific reports2016

2, 3-Dimethylmaleic anhydride (3, 4-Dimethyl-2, 5-furandione): A plant derived insecticidal molecule from Colocasia esculenta var. esculenta (L.) Schott.

Yallappa Rajashekar, Ngaihlun Tonsing, Tourangbam Shantibala, Javagal R Manjunath

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Journal of experimental pharmacology · 2025
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Insecticidal and biochemical effects ofFrontiers in plant science · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Tarin, a Potential Immunomodulator and COX-Inhibitor Lectin Found in Taro (Comprehensive reviews in food science and food safety · 2018
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yallappa RajashekarAnimal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
Ngaihlun TonsingAnimal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
Tourangbam ShantibalaAnimal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
Javagal R ManjunathDepartment of Spice &Flavour Science, Central Food Technological Research Institute, Mysore-570020, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phasing out of methyl bromide as a fumigant, resistance problems with phosphine and other fumigants in stored product beetles, and serious concern with human health and environmental safety have triggered the search for alternative biofumigants of plant origin. Despite the identification of a large number of plants that show insecticidal activity, and the diversity of natural products with inherent eco-friendly nature, newer biofumigants of plant origin have eluded discovery. Using a bioassay driven protocol, we have now isolated a bioactive molecule from the root stock of Colocasia esculenta (L.) and characterized it as 2, 3-dimethylmaleic anhydride (3, 4-dimethyl-2, 5-furandione) based on various physico-chemical and spectroscopic techniques (IR, (1)H NMR, (13)C NMR and Mass). The molecule proved to be an efficient biofumigant which is highly toxic to insect pests for stored grains even at very low concentration, but has no adverse effect on seed germination. We finally address the potential for this molecule to become a, effective biofumigant.

Indexed as

AnhydridesAnimalsColeopteraColocasiaFuransGerminationMolecular StructurePesticidesPlant ExtractsPlant RootsAnhydridesFuransPesticidesPlant Extracts

Identifiers

PMID26837840
PMCPMC4738332

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.