Evidence map›Paper›PMID 26837461›Full record

ArticleThe American journal of drug and alcohol abuse2016

The impact of age, HIV serostatus and seroconversion on methamphetamine use.

Jessica L Montoya, Jordan Cattie, Erin Morgan, Steven Paul Woods, Mariana Cherner, David J Moore, J Hampton Atkinson, Igor Grant, Translational Methamphetamine Aids Research Center (TMARC) Group

Open access · greenAbstract read
In one paragraph

Article in The American journal of drug and alcohol abuse, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. HIV Neuropathogenesis in the Presence of a Disrupted Dopamine System.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2020
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Effects of HIV and Methamphetamine on Brain and Behavior: Evidence from Human Studies and Animal Models.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2016
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jessica L Montoyaa Clinical Psychology, San Diego State University/University of California, San Diego Joint Doctoral Program , San Diego , CA , USA.
Jordan Cattiea Clinical Psychology, San Diego State University/University of California, San Diego Joint Doctoral Program , San Diego , CA , USA.
Erin Morganb Translational Methamphetamine AIDS Research Center, Department of Psychiatry , School of Medicine, University of California, San Diego , La Jolla , CA , USA.
Steven Paul Woodsb Translational Methamphetamine AIDS Research Center, Department of Psychiatry , School of Medicine, University of California, San Diego , La Jolla , CA , USA.
Mariana Chernerb Translational Methamphetamine AIDS Research Center, Department of Psychiatry , School of Medicine, University of California, San Diego , La Jolla , CA , USA.
David J Mooreb Translational Methamphetamine AIDS Research Center, Department of Psychiatry , School of Medicine, University of California, San Diego , La Jolla , CA , USA.
J Hampton Atkinsonb Translational Methamphetamine AIDS Research Center, Department of Psychiatry , School of Medicine, University of California, San Diego , La Jolla , CA , USA.
Igor Grantb Translational Methamphetamine AIDS Research Center, Department of Psychiatry , School of Medicine, University of California, San Diego , La Jolla , CA , USA.
Translational Methamphetamine Aids Research Center (TMARC) Groupc VA San Diego Healthcare System , San Diego , CA , USA.
University of California, San Diego · USVA San Diego Healthcare System · US

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAVID J MOORE · 2001 to 2026
$50.4M
Translational Methamphetamine AIDS Research Center (TMARC)P50DA026306 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GRANT, IGOR · 2009 to 2018
$33.9M
Novel Proteomics Approach to HIV-Associated Neurocognitive Disorder & Drug AbuseDP1DA041722 · NIDA · SCRIPPS RESEARCH INSTITUTE, THE · PI LIPTON, STUART A · 2016 to 2020
$7.0M
Multi-Dimensional Successful Aging Among HIV-Infected AdultsR01MH099987 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JESTE, DILIP V., MOORE, DAVID J · 2013 to 2019
$3.8M
Mentoring Clinical Researchers at the Intersection of NeuroHIV and Substance AbuseK24DA040550 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHERNER, MARIANA · 2015 to 2025
$1.8M
NIDA NIH HHS DP1 DA041722NIDA NIH HHS K24 DA040550NIDA NIH HHS P50 DA026306NIDA NIH HHS P50-DA026306NIMH NIH HHS P30 MH062512NIMH NIH HHS R01 MH099987NIMH NIH HHS R01 MH099987-02S1
6 · The paper itself

Abstract

backgroundCharacterizing methamphetamine use in relation to age, HIV serostatus and seroconversion is pertinent given the increasingly older age of the population with HIV and the intertwined epidemics of methamphetamine use and HIV.

objectivesStudy aims were to investigate whether (i) methamphetamine use differs by age and HIV serostatus, and (ii) receiving an HIV diagnosis impacts methamphetamine use among younger and older persons with HIV.

methodsThis study examined methamphetamine use characteristics among 217 individuals with a lifetime methamphetamine dependence diagnosis who completed an in-person study assessment.

resultsMultivariable regressions revealed that HIV serostatus uniquely attenuates methamphetamine use, such that persons with HIV report a smaller cumulative quantity (β = -0.16, p = 0.01) and a fewer number of days (β = -0.18, p = 0.004) of methamphetamine use than persons without HIV. Among the HIV+ sample, all participants persisted in methamphetamine use after receiving an HIV diagnosis, with about 20% initiating use after seroconversion. Repeated measures analysis of variance indicated that density of methamphetamine use (i.e. grams per day used) was greater among the younger, relative to the older, HIV+ group (p = 0.02), and increased for both age groups following seroconversion (p < 0.001).

conclusionThese analyses indicate that although HIV serostatus may attenuate methamphetamine use behaviors, many people with HIV initiate, or persist in, methamphetamine use after receiving an HIV diagnosis. These findings raise the question of whether tailoring of prevention and intervention strategies might reduce the impact of methamphetamine and HIV across the age continuum.

Indexed as

AIDS SerodiagnosisSeroconversionAdultAgingAmphetamine-Related DisordersFemaleHIV InfectionsHumansMaleMethamphetamineMiddle AgedRisk-TakingYoung AdultMethamphetamineageHIV/AIDSHIV risk behaviorMethamphetaminestimulant

Identifiers

PMID26837461
PMCPMC4842208
OpenAlexW2288527648

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.