Evidence map›Paper›PMID 26837437›Full record

ArticleAIDS care2016

Evaluating mental health difficulties and associated outcomes among HIV-positive adolescents in Tanzania.

Dorothy E Dow, Elizabeth L Turner, Aisa M Shayo, Blandina Mmbaga, Coleen K Cunningham, Karen O'Donnell

3 registry-linked trialsAbstract read
In one paragraph

Article in AIDS care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 110 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02888288 nacompletednot on this map

Integrating Mental Health Into a HIV Clinic to Improve Outcomes Among Tanzanian Youth

TypeinterventionalSponsorDuke UniversityRan2016 to 2020Enrolled140ConditionsHealth Behavior, HIV, Mental HealthArmsMental Health Intervention, Standard of Care
NCT04115813 nacompletednot on this mapstarted 2017, after this paper: background citation

Transitioning Adolescents to HIV Self-Management in Zambia (Known as: Project YES: Youth Engaging for Success)

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2017 to 2019Enrolled276ConditionsHIV/AIDSArmsProject YES! Youth Engaging for Success
NCT07221201 nacompletednot on this mapstarted 2025, after this paper: background citation

Reducing the Intersecting Stigmas of HIV, Violence Victimization, and Mental Health: a Randomized Controlled Pilot Integrating Project YES! Youth Engaging for Success With WHO-Endorsed Mental Health Approaches Among Youth Living With HIV in Ndola, Zambia

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2025 to 2026Enrolled323ConditionsHIV - Human Immunodeficiency Virus, Mental Health, Anxiety, Depression in AdolescenceArmsProject YES+ intervention arm
3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dorothy E Dowa Division of Pediatric Infectious Diseases , Duke University Medical Center , Durham , NC , USA.
Elizabeth L Turnerc Duke Global Health Institute, Duke University , Durham , NC , USA.
Aisa M Shayob Kilimanjaro Christian Medical Centre , Moshi , Tanzania.
Blandina Mmbagab Kilimanjaro Christian Medical Centre , Moshi , Tanzania.
Coleen K Cunninghama Division of Pediatric Infectious Diseases , Duke University Medical Center , Durham , NC , USA.
Karen O'Donnelle Center for Health Policy and Inequalities Research , Duke University , Durham , NC , USA.

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI GEORGIA Doris TOMARAS · 2005 to 2026
$50.5M
Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
Institutional Training Grant in Pediatric Infectious DiseaseT32HD060558 · NICHD · DUKE UNIVERSITY · PI CUNNINGHAM, COLEEN K. · 2011 to 2015
$1.0M
Integrating Mental Health into a HIV Clinic to Improve Outcomes in Tanzanian YouthK01TW009985 · FIC · DUKE UNIVERSITY · PI DOW, DOROTHY E. · 2015 to 2019
$667k
FIC NIH HHS K01 TW009985FIC NIH HHS R25 TW009337NIAID NIH HHS P30 AI064518NICHD NIH HHS T32 HD060558
6 · The paper itself

Abstract

AIDS-related mortality among HIV-positive adolescents has risen by 50% despite the scale up of antiretroviral therapy (ART). ART maladherence likely plays a role in the increase of AIDS-related deaths among adolescents and has shown to be associated with psychosocial and mental health difficulties. Addressing the specific mental health needs of HIV-positive adolescents is critical to ending the HIV epidemic. This cross-sectional study prospectively enrolled HIV-positive adolescents (12-24 years) in Moshi, Tanzania. A structured questionnaire was administered that included questions about home, school, adherence, and measures of stigma (Berger Stigma Scale) and mental health. Mental health measures included depression (Patient Health Questionnaire-9), emotional/behavioral difficulties (Strengths and Difficulties Questionnaire), and traumatic experiences/post-traumatic stress symptoms (The University of California Los Angeles-post-traumatic stress disorder-Reaction Index). Mental health difficulties were prevalent among HIV-positive adolescents and were associated with incomplete adherence and stigma. Resources are needed to reduce HIV stigma and address mental health among HIV-positive adolescents in low-resource settings. This will improve not only mental health, but may also improve ART adherence and virologic suppression, improving overall health of the individual and reducing the risk of HIV transmission to others.

Indexed as

HIV InfectionsAdolescentCross-Sectional StudiesDepressionDrug MonitoringFemaleHumansMaleMedication AdherenceMental HealthNeeds AssessmentPrevalenceSocial StigmaStress Disorders, Post-TraumaticSurveys and QuestionnairesTanzaniaadolescent mental healthantiretroviral therapy adherencedepressionPediatric HIVtrauma

Identifiers

PMID26837437
PMCPMC4905805

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.