ReviewChest2016
Persistent Challenges in Pediatric Pulmonary Hypertension.
Review in Chest, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk Factors and Outcomes of Pulmonary Hypertension in Infants With Bronchopulmonary Dysplasia: A Meta-Analysis.Frontiers in pediatrics · 2021Pooled it
- Child Opportunity Index Influences Pediatric Pulmonary Hypertension Outcomes: Analyses From the Pediatric Health Information System.JACC. Advances · 2026Article
- Missed or Delayed Diagnosis of Heart Disease by the General Pediatrician.Children (Basel, Switzerland) · 2025Review
- Precision Medicine for Pulmonary Vascular Disease: The Future Is Now (2023 Grover Conference Series).Pulmonary circulation · 2025Article
- Extracorporeal membrane oxygenation (ECMO) support for children with pulmonary hypertension: A single-institutional experience of outcomes.Pulmonary circulation · 2024Article
- Idiopathic Pulmonary Arterial Hypertension in Paediatrics Represents Still a Serious Challenge: A Case Series Study.Children (Basel, Switzerland) · 2023Article
- AMPK deficiency in smooth muscles causes persistent pulmonary hypertension of the new-born and premature death.Nature communications · 2022Article
- Explainable machine learning models for predicting 30-day readmission in pediatric pulmonary hypertension: A multicenter, retrospective study.Frontiers in cardiovascular medicine · 2022Article
- BCAT1 binds the RNA-binding protein ZNF423 to activate autophagy via the IRE1-XBP-1-RIDD axis in hypoxic PASMCs.Cell death & disease · 2020Article
- Differences in pulmonary arterial flow hemodynamics between children and adults with pulmonary arterial hypertension as assessed by 4D-flow CMR studies.American journal of physiology. Heart and circulatory physiology · 2019Article
- Proximal pulmonary vascular stiffness as a prognostic factor in children with pulmonary arterial hypertension.European heart journal. Cardiovascular Imaging · 2019Article
- Noninvasive wave intensity analysis predicts functional worsening in children with pulmonary arterial hypertension.American journal of physiology. Heart and circulatory physiology · 2018Article
- Measuring Flow Hemodynamic Indices and Oxygen Consumption in Children with Pulmonary Hypertension: A Comparison of Catheterization and Phase-Contrast MRI.Pediatric cardiology · 2018Article
- Mid-childhood outcomes after pre-viable preterm premature rupture of membranes.Journal of perinatology : official journal of the California Perinatal Association · 2017Article
- Pulmonary arterial hypertension in the USA: an epidemiological study in a large insured pediatric population.Pulmonary circulation · 2017Article
- Apparent Aortic Stiffness in Children With Pulmonary Arterial Hypertension: Existence of Vascular Interdependency?Circulation. Cardiovascular imaging · 2017Article
- Right ventricular stroke work correlates with outcomes in pediatric pulmonary arterial hypertension.Pulmonary circulationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Pulmonary hypertension and related pulmonary vascular diseases cause significant morbidities and high mortality and present many unique challenges toward improving outcomes in neonates, infants, and children. Differences between pediatric and adult disease are reflected in controversies regarding etiologies, classification, epidemiology, diagnostic evaluations, and therapeutic interventions. This brief review highlights several key topics reflecting recent advances in the field and identifies persistent gaps in our understanding of clinical pediatric pulmonary hypertension.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.