Evidence map›Paper›PMID 26836902›Full record

ArticleChest2016

Hospitals' Patterns of Use of Noninvasive Ventilation in Patients With Asthma Exacerbation.

Mihaela S Stefan, Brian H Nathanson, Aruna Priya, Penelope S Pekow, Tara Lagu, Jay S Steingrub, Nicholas S Hill, Robert J Goldberg, David M Kent, Peter K Lindenauer

Open access · bronzeAbstract read
In one paragraph

Article in Chest, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Noninvasive Ventilation for Acute Asthma: The Neglected Sibling.American journal of respiratory and critical care medicine · 2020
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Response.Chest · 2016
    Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mihaela S StefanCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA; Division of Hospital Medicine, Baystate Medical Center, Springfield, MA; Department of Medicine, Tufts University School of Medicine, Boston, MA. Electronic address: mihaela.stefan@baystatehealth.org.
Brian H NathansonOptiStatim LLC, Longmeadow, MA.
Aruna PriyaCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA.
Penelope S PekowCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA; School of Public Health & Health Sciences, University of Massachusetts Amherst, Amherst, MA.
Tara LaguCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA; Division of Hospital Medicine, Baystate Medical Center, Springfield, MA; Department of Medicine, Tufts University School of Medicine, Boston, MA.
Jay S SteingrubDivision of Pulmonary and Critical Care, Baystate Medical Center, Springfield, MA.
Nicholas S HillDivision of Pulmonary and Critical Care Medicine, Tufts University School of Medicine, Boston, MA.
Robert J GoldbergDepartment of Quantitative Health Sciences, UMass Medical School, Worcester, MA.
David M KentInstitute for Clinical Research and Health Policy Studies, Tufts University School of Medicine, Boston, MA.
Peter K LindenauerCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA; Division of Hospital Medicine, Baystate Medical Center, Springfield, MA; Department of Medicine, Tufts University School of Medicine, Boston, MA.
Baystate Medical Center · USTufts University · USUniversity of Massachusetts Chan Medical School · US

Funding

Defining Optimal Clinical Strategies for Critically Ill Heart Failure PatientsK01HL114745 · NHLBI · BAYSTATE MEDICAL CENTER, INC. · PI LAGU, TARA C · 2013 to 2017
$721k
Comparing Noninvasive and Invasive Ventilation in Acute Respiratory FailureK01HL114631 · NHLBI · BAYSTATE MEDICAL CENTER, INC. · PI STEFAN, MIHAELA S · 2013 to 2016
$565k
NHLBI NIH HHS 1K01HL114631-01A1NHLBI NIH HHS K01 HL114631NHLBI NIH HHS K01 HL114745
6 · The paper itself

Abstract

backgroundLimited data are available on the use of noninvasive ventilation in patients with asthma exacerbations. The objective of this study was to characterize hospital patterns of noninvasive ventilation use in patients with asthma and to evaluate the association with the use of invasive mechanical ventilation and case fatality rate.

methodsThis cross-sectional study used an electronic medical record dataset, which includes comprehensive pharmacy and laboratory results from 58 hospitals. Data on 13,558 patients admitted from 2009 to 2012 were analyzed. Initial noninvasive ventilation (NIV) or invasive mechanical ventilation (IMV) was defined as the first ventilation method during hospitalization. Hospital-level risk-standardized rates of NIV among all admissions with asthma were calculated by using a hierarchical regression model. Hospitals were grouped into quartiles of NIV to compare the outcomes.

resultsOverall, 90.3% of patients with asthma were not ventilated, 4.0% were ventilated with NIV, and 5.7% were ventilated with IMV. Twenty-two (38%) hospitals did not use NIV for any included admissions. Hospital-level adjusted NIV rates varied considerably (range, 0.4-33.1; median, 5.2%). Hospitals in the highest quartile of NIV did not have lower IMV use (5.4% vs 5.7%), but they did have a small but significantly shorter length of stay. Higher NIV rates were not associated with lower risk-adjusted case fatality rates.

conclusionsLarge variation exists in hospital use of NIV for patients with an acute exacerbation of asthma. Higher hospital rates of NIV use does not seem to be associated with lower IMV rates. These results indicate a need to understand contextual and organizational factors contributing to this variability.

Indexed as

AsthmaBronchodilator AgentsComorbidityCross-Sectional StudiesDatabases, FactualDisease ProgressionElectronic Health RecordsFemaleGlucocorticoidsHealth Facility SizeHospitalizationHospitals, RuralHospitals, TeachingHospitals, UrbanHumansLogistic ModelsBronchodilator AgentsGlucocorticoidsasthmaCPAPmechanical ventilationnoninvasive ventilation

Identifiers

PMID26836902
PMCPMC4944771
OpenAlexW2297260804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.