ArticleTranslational psychiatry2016
MAP training: combining meditation and aerobic exercise reduces depression and rumination while enhancing synchronized brain activity.
Article in Translational psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06123559 (Effects of Physical Exercise and Motor Activity on Depression and Anxiety in Post-Mastectomy Pain Syndrome), which is not on this map. Cited by 51 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Physical Exercise and Motor Activity on Depression and Anxiety in Post-Mastectomy Pain Syndrome
Who cites it
51 citing papers in PubMed, 5 syntheses or guidelines pooled it, 118 citations in OpenAlex.
- Comparative efficacy of various mind-body exercise types on cardiometabolic health in patients with type 2 diabetes: a network meta-analysis of randomized controlled trials.BMC cardiovascular disorders · 2025Pooled it
- Does physical activity-based intervention decrease repetitive negative thinking? A systematic review.PloS one · 2025Pooled it
- Effect of different physical activity interventions on perinatal depression: a systematic review and network meta-analysis.BMC public health · 2024Pooled it
- Cognition, body, and mind: A three-in-one coordinate-based fMRI meta-analysis on cognitive, physical, and meditative trainings.Human brain mapping · 2023Pooled it
- Exercise for Cognitive Symptoms in Depression: A Systematic Review of Interventional Studies.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2018Pooled it
- Mindfulness-based (non-contact) boxing therapy (MBBT) for depression and anxiety: A feasibility study.PloS one · 2025Trial
- Integrated Meditation and Exercise Therapy: A Randomized Controlled Pilot of a Combined Nonpharmacological Intervention Focused on Reducing Disability and Pain in Patients with Chronic Low Back Pain.Pain medicine (Malden, Mass.) · 2021Trial
- Reduced task-switching flexibility in parietal-cingulate and frontal circuits associated with brooding.Cognitive neurodynamics · 2026Article
- Mechanisms of Exercise Training in Ameliorating Cognitive Function in Patients With Depression: A Narrative Review of Molecular Targets and Clinical Prescriptions.European journal of sport science · 2026Review
- Article
- Exercise intervention for rumination: from neural mechanisms to clinical applications.Frontiers in psychology · 2026Review
- Physical Therapy for Treatment-Resistant Depression A Comprehensive Review of Efficacy, Safety, and Evidence Grading.Neuropsychiatric disease and treatment · 2026Review
- Physical activity and executive function in adolescents: Dual rumination pathways and mindfulness moderation.PloS one · 2026Article
- Bidirectional regulatory effects of exercise on emotional eating in depression: an ERP-based narrative review.Frontiers in nutrition · 2026Review
- The mediating role of rumination and psychological resilience between physical activity and sleep quality among college students.Scientific reports · 2025Article
- The Relationship Between Different Components and Levels of Physical Exercise, Depressive Symptoms, Inhibitory Control, and Possible Cognitive Neural Mechanisms in College Students.CNS neuroscience & therapeutics · 2025Observational
- The impact of physical activity on subjective well-being in college students: the mediating role of rumination and the moderating role of behavioral activation/inhibition systems.BMC psychology · 2025Article
- Determining the feasibility and acceptability of a randomized telehealth pilot study for veterans with chronic multisymptom illness.Pilot and feasibility studies · 2025Article
- High-level personal trainer perspective for industry practice and development in Serbia: a qualitative descriptive study.Frontiers in sports and active living · 2025Article
- The Impact of Physical Exercise on Sleep Quality Among College Students: The Chain Mediating Effects of Perceived Stress and Ruminative Thinking.Psychology research and behavior management · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mental and physical (MAP) training is a novel clinical intervention that combines mental training through meditation and physical training through aerobic exercise. The intervention was translated from neuroscientific studies indicating that MAP training increases neurogenesis in the adult brain. Each session consisted of 30 min of focused-attention (FA) meditation and 30 min of moderate-intensity aerobic exercise. Fifty-two participants completed the 8-week intervention, which consisted of two sessions per week. Following the intervention, individuals with major depressive disorder (MDD; n=22) reported significantly less depressive symptoms and ruminative thoughts. Typical healthy individuals (n=30) also reported less depressive symptoms at follow-up. Behavioral and event-related potential indices of cognitive control were collected at baseline and follow-up during a modified flanker task. Following MAP training, N2 and P3 component amplitudes increased relative to baseline, especially among individuals with MDD. These data indicate enhanced neural responses during the detection and resolution of conflicting stimuli. Although previous research has supported the individual beneficial effects of aerobic exercise and meditation for depression, these findings indicate that a combination of the two may be particularly effective in increasing cognitive control processes and decreasing ruminative thought patterns.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.