ArticleJournal of the American Chemical Society2016
Asymmetric Catalysis with a Mechanically Point-Chiral Rotaxane.
Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed.
- A General and Scalable Chiral Surrogate Rotaxane Strategy for Highly Enantioenriched Mechanically Planar Chiral Rotaxanes.Angewandte Chemie (International ed. in English) · 2026Article
- A Redox-active Cyclometalated Platinum Ring Enables Synthetic Post-processing of a [2]Rotaxane.Angewandte Chemie (International ed. in English) · 2025Article
- The End of the Beginning of Mechanical Stereochemistry.Accounts of chemical research · 2024Article
- Facial Selectivity in Mechanical Bond Formation: Axially Chiral Enantiomers and Geometric Isomers from a Simple Prochiral Macrocycle.Journal of the American Chemical Society · 2024Article
- Kinetically controlled synthesis of rotaxane geometric isomers.Chemical science · 2024Article
- One-pot asymmetric living copolymerization-induced chiral self-assemblies and circularly polarized luminescence.Chemical science · 2024Article
- Into the dynamics of rotaxanes at atomistic resolution.Chemical science · 2023Article
- Tailored Supramolecular Cage for Efficient Bio-Labeling.International journal of molecular sciences · 2023Article
- A light-gated regulation of the reaction site by a cucurbit[7]uril macrocycle.Chemical science · 2022Article
- Ring-to-Thread Chirality Transfer in [2]Rotaxanes for the Synthesis of Enantioenriched Lactams.Angewandte Chemie (International ed. in English) · 2022Article
- Mechanically axially chiral catenanes and noncanonical mechanically axially chiral rotaxanes.Nature chemistry · 2022Article
- A Co-conformationally "Topologically" Chiral Catenane.Journal of the American Chemical Society · 2022Article
- Anion-π Catalysis Enabled by the Mechanical Bond.Angewandte Chemie (International ed. in English) · 2022Article
- Controlling catalyst activity, chemoselectivity and stereoselectivity with the mechanical bond.Nature reviews. Chemistry · 2022Review
- Rotaxanes with dynamic mechanical chirality: Systematic studies on synthesis, enantiomer separation, racemization, and chiral-prochiral interconversion.Frontiers in chemistry · 2022Article
- Mechanically Interlocked Chiral Self-Templated [2]Catenanes from 2,6-Bis(1,2,3-triazol-4-yl)pyridine (btp) Ligands.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- Stereodynamics ofChem · 2021Article
- Using the Mechanical Bond to Tune the Performance of a Thermally Activated Delayed Fluorescence Emitter*.Angewandte Chemie (International ed. in English) · 2021Article
- Spin-labelled mechanically interlocked molecules as models for the interpretation of biradical EPR spectra.Chemical science · 2021Article
- Functional Rotaxanes in Catalysis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Mechanical point-chirality in a [2]rotaxane is utilized for asymmetric catalysis. Stable enantiomers of the rotaxane result from a bulky group in the middle of the thread preventing a benzylic amide macrocycle shuttling between different sides of a prochiral center, creating point chirality in the vicinity of a secondary amine group. The resulting mechanochirogenesis delivers enantioselective organocatalysis via both enamine (up to 71:29 er) and iminium (up to 68:32 er) activation modes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.