ReviewDiagnostics (Basel, Switzerland)2013
A Review of Heating and Temperature Control in Microfluidic Systems: Techniques and Applications.
Review in Diagnostics (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed.
- 3D-printed thermoregulator and magnetic stirrer device.HardwareX · 2026Article
- Integrating Low-Voltage Microfluidics With On-Chip Electrospray Ionization for Miniaturized Protein Analysis.Small methods · 2026Review
- From Simulation to Application: Droplet-Based Microfluidics for Thermal Targeting of Cancer Cells.Micromachines · 2026Article
- Thermal Recovery of Damaged Hydrophobic Coatings in EWOD Devices Using an Integrated Mesh-Patterned Heater.Micromachines · 2026Article
- Rapid and precise temperature control of samples flowing through a capillary from -20 to 130 °C.The Review of scientific instruments · 2026Article
- Microfluidic Platforms for Cryopreservation.Methods in molecular biology (Clifton, N.J.) · 2026Article
- 3D Printed Microfluidic Device for Combined Thermal and Fluorescence Analysis.Microfluidics and nanofluidics · 2025Article
- Thermoregulable Magnetic Microfluidic Devices by Magnetic Hyperthermia from Iron Oxide Nanoparticles.ACS applied nano materials · 2025Article
- Advanced microfluidic systems with temperature modulation for biological applications.Biomicrofluidics · 2025Article
- A novel Complex q-rung orthopair fuzzy Yager aggregation operators and their applications in environmental engineering.Heliyon · 2025Article
- Microfluidics for the biological analysis of atmospheric ice-nucleating particles: Perspectives and challenges.Biomicrofluidics · 2025Review
- Chemical Heating for Minimally Instrumented Point-of-Care (POC) Molecular Diagnostics.Biosensors · 2024Review
- Dynamic temperature control in microfluidics for in vivo imaging of cold-sensing in C. elegans.Biophysical journal · 2024Article
- Low-Cost Arduino Reverse Transcriptase Loop-Mediated Isothermal Amplification (RT-LAMP) for Sensitive Nucleic Acid Detection.Biosensors · 2024Article
- Using Recurrent Neural Networks to Reconstruct Temperatures from Simulated Fluorescent Data for use in Bio-Microfluidics.International journal of thermophysics · 2023Article
- Microsystem Advances through Integration with Artificial Intelligence.Micromachines · 2023Review
- Portable in situ temperature-dependent spectroscopy on a low-cost microfluidic platform integrated with a battery-powered thermofoil heater.View (Beijing, China) · 2023Article
- Recent advances and challenges in temperature monitoring and control in microfluidic devices.Electrophoresis · 2023Review
- Droplet microreactor for high-throughput fluorescence-based measurements of single catalyst particle acidity.Microsystems & nanoengineering · 2023Article
- Microfluidics for multiscale studies of biomolecular condensates.Lab on a chip · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review presents an overview of the different techniques developed over the last decade to regulate the temperature within microfluidic systems. A variety of different approaches has been adopted, from external heating sources to Joule heating, microwaves or the use of lasers to cite just a few examples. The scope of the technical solutions developed to date is impressive and encompasses for instance temperature ramp rates ranging from 0.1 to 2,000 °C/s leading to homogeneous temperatures from -3 °C to 120 °C, and constant gradients from 6 to 40 °C/mm with a fair degree of accuracy. We also examine some recent strategies developed for applications such as digital microfluidics, where integration of a heating source to generate a temperature gradient offers control of a key parameter, without necessarily requiring great accuracy. Conversely, Temperature Gradient Focusing requires high accuracy in order to control both the concentration and separation of charged species. In addition, the Polymerase Chain Reaction requires both accuracy (homogeneous temperature) and integration to carry out demanding heating cycles. The spectrum of applications requiring temperature regulation is growing rapidly with increasingly important implications for the physical, chemical and biotechnological sectors, depending on the relevant heating technique.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.