ArticleCancer biomarkers : section A of Disease markers2016
Podoplanin serum and urine concentration in transitional bladder cancer.
Article in Cancer biomarkers : section A of Disease markers, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 35 citations in OpenAlex.
- Biomarkers for Recurrence and Prognosis in Metastatic Urothelial Cancer: Emerging Clinical Applications.Journal of Cancer · 2026Review
- New Challenges in Bladder Cancer Diagnosis: How Biosensing Tools Can Lead to Population Screening Opportunities.Sensors (Basel, Switzerland) · 2024Review
- An Array SPRi Biosensor for the Determination of Follicle-Stimulating Hormone in Blood Plasma.Sensors (Basel, Switzerland) · 2023Article
- Podoplanin: A potential therapeutic target for thrombotic diseases.Frontiers in neurology · 2023Review
- An Immunosensor for the Determination of Cortisol in Serum and Saliva by Array SPRi.Sensors (Basel, Switzerland) · 2022Article
- Two Biosensors for the Determination of Interleukin-6 in Blood Plasma by Array SPRi.Biosensors · 2022Article
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- The Detection of Plasma Soluble Podoplanin of Patients with Breast Cancer and Its Clinical Signification.Cancer management and research · 2020Article
- Plasma aromatase as a sensitive and selective potential biomarker of bladder cancer and its role in tumorigenesis.Oncology letters · 2020Article
- Podoplanin in Inflammation and Cancer.International journal of molecular sciences · 2019Review
- Review
- Plasma soluble podoplanin is a novel marker for the diagnosis of tumor occurrence and metastasis.Cancer science · 2018Article
- Immunoproteasome in the blood plasma of children with acute appendicitis, and its correlation with proteasome and UCHL1 measured by SPR imaging biosensors.Clinical and experimental immunology · 2018Article
- Methods for 20S Immunoproteasome and 20S Constitutive Proteasome Determination Based on SPRI Biosensors.Cellular and molecular bioengineering · 2017Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPodoplanin (PDP) is a mucin - a type of transmembrane protein expressed in numerous tissues during ontogeny and in adult animals, including the brain, heart, kidney, osteoblasts and lymphoid organs.
objectiveThe aim of this study was to determine podoplanin concentration in the blood serum and urine of patients with bladder cancer. Quantifying podoplanin concentration and its correlation with various clinicopathological parameters may be useful for more accurate predictions and identifying high-risk patients.
methodsThe present study included 82 patients with bladder cancer confirmed by transurethral resection or cystectomy and 27 healthy volunteers. The Surface Plasmon Resonance Imaging biosensor was applied for the detection of podoplanin in the serum and urine samples.
resultsSignificant differences in serum and urine podoplanin concentration levels were observed between bladder cancer patients. The statistically significant higher values of PDP were detected in serum of patients with invasive, more aggressive, larger, multifocal tumors.
conclusionsThe association between podoplanin concentration and clinicopathological features indicates that it might be useful while making therapeutic decisions.
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