Evidence map›Paper›PMID 26834967›Full record

ArticleTherapeutic advances in psychopharmacology2015

Nurses' perceptions of medication adherence in schizophrenia: results of the ADHES cross-sectional questionnaire survey.

Robin Emsley, Koksal Alptekin, Jean-Michel Azorin, Fernando Cañas, Vincent Dubois, Philip Gorwood, Peter M Haddad, Dieter Naber, José Manuel Olivares, Georgios Papageorgiou and 5 more

Open access · greenAbstract read
In one paragraph

Article in Therapeutic advances in psychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 8 countries.

Robin EmsleyDepartment of Psychiatry, University of Stellenbosch, Tygerberg 7505, Cape Town, South Africa.
Koksal AlptekinDepartment of Psychiatry, Dokuz Eylül University School of Medicine, Izmir, Turkey.
Jean-Michel AzorinSHU Psychiatrie Adultes, Sainte Marguerite Hospital, Marseilles, France.
Fernando CañasDepartment of Psychiatry, Hospital Dr R Lafora, Cra de Colmenar Viejo, Madrid, Spain.
Vincent DuboisService de psychiatrie adulte, Cliniques universitaires St-Luc, Bruxelles, Belgium.
Philip GorwoodCMME, Hôpital Sainte-Anne (Paris Descartes), Paris, France.
Peter M HaddadGreater Manchester West Mental Health NHS Foundation Trust and Department of Psychiatry, University of Manchester, Manchester, UK.
Dieter NaberKlinik für Psychiatrie und Psychotherapie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
José Manuel OlivaresDepartment of Psychiatry, Hospital Meixoeiro, Complejo Hospitalario Universitario de Vigo, Vigo, Spain.
Georgios PapageorgiouDepartment of Psychiatry, Evangelismos General Hospital, Athens, Greece.
Miguel RocaUnidad de Psiquiatría, Hospital Juan March, Institut Universitari d'Investigació en Ciències de la Salut (IUNICS), Universitat de les Illes Balears, Palma de Mallorca, Spain.
Pierre ThomasService de Psychiatrie, Hôpital M. Fontan, Lille, France.
Ludger HargarterDepartment of Medical and Scientific Affairs, Janssen EMEA, Neuss, Germany.
Andreas SchreinerDepartment of Medical and Scientific Affairs, Janssen EMEA, Neuss, Germany.
EMEA ADHES group
Janssen (Germany) · DECliniques Universitaires Saint-Luc · BEDélégation Paris 5 · FRDokuz Eylül University · TREvangelismos Hospital · GRGreater Manchester Mental Health NHS Foundation Trust · GBHôpital Fontmaure · FRHôpital Sainte-Marguerite · FRResearch Institute of Health Sciences · ESStellenbosch University · ZAUniversität Hamburg · DEUniversity Hospital Complex Of Vigo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPoor adherence to antipsychotic treatment is a widespread problem within schizophrenia therapy with serious consequences including increased risks of relapse and rehospitalization. Mounting evidence supports the key roles that nurses play in monitoring patient progress and facilitating long-term treatment adherence. The Adherencia Terapéutica en la Esquizofrenia (ADHES) nurses' survey was designed to assess the opinions of nurses on the causes and management of partial/nonadherence to antipsychotic medication.

methodsA questionnaire-based cross-sectional survey of 4120 nurses from Europe, the Middle East and Africa. Interpretation of results was based on a descriptive comparison of responses.

resultsNurses perceived 54% of patients seen in the preceding month to be partially/nonadherent to treatment. Most nurses (90%) reported some level of experience with administration of long-acting injectable (LAI) antipsychotics, with 24% of nurses administering >10 injections per month. The majority (85%) of nurses surveyed believed that improving adherence would improve patient outcomes. Nearly half (49%) reported that most of their patients depend on a family member or other nonprofessional carer to remind them to take their medication as prescribed. A similar proportion of nurses (43%) reported that most of their patients relied on a professional to remind them to take medication. Most nurses (92%) felt that ensuring continuous medication with LAI antipsychotics would yield long-term benefits for patients, but their opinion was that over a third of patients were unaware of LAI antipsychotic treatments. In a series of forced options, the strategy used most often by respondents (89%) to promote medication adherence was to build trusting relationships with patients while listening to and interpreting their needs and concerns. Respondents also rated this as the most effective strategy that they used (48%).

conclusionNurses are highly aware of adherence issues faced by their patients; further patient education on treatment options is needed.

Indexed as

adherenceantipsychoticnurseschizophreniasurvey

Identifiers

PMID26834967
PMCPMC4722504
OpenAlexW2286581754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.