ReviewFrontline gastroenterology2016
Response to the NCEPOD report: development of a care bundle for patients admitted with decompensated cirrhosis-the first 24 h.
Review in Frontline gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 51 citations in OpenAlex.
- Cause-specific mortality among Queensland people with cirrhosis, by cirrhosis aetiology and decompensation status, 2007-22: a retrospective cohort study.The Medical journal of Australia · 2025Article
- Management of acute decompensated cirrhosis.Clinical medicine (London, England) · 2025Review
- 3PM-guided innovation in treatments of severe alcohol-associated hepatitis utilizing fecal microbiota transplantation.The EPMA journal · 2024Article
- Regional variations in inpatient decompensated cirrhosis mortality may be associated with access to specialist care: results from a multicentre retrospective study.Frontline gastroenterology · 2024Article
- Observational
- Admission care bundles for decompensated cirrhosis are poorly utilised across the UK: results from a multi-centre retrospective study.Clinical medicine (London, England) · 2023Observational
- The BSG/BASL bundle for patients admitted with decompensated chronic liver disease improves standard of care but utilisation is poor across the UK.Clinical medicine (London, England) · 2022Article
- Improved outcomes following the implementation of a decompensated cirrhosis discharge bundle.Frontline gastroenterology · 2022Article
- ToRcH-UK: shining a light on liver disease in the UK.Frontline gastroenterology · 2022Article
- Use of FFP to correct INR: time to drop this from the decompensated cirrhosis care bundle?Frontline gastroenterology · 2022Article
- Implementation of a care bundle improves the management of patients with non-alcoholic fatty liver disease.Frontline gastroenterology · 2021Article
- Increased cardiovascular risk and reduced quality of life are highly prevalent among individuals with hepatitis C.BMJ open gastroenterology · 2020Observational
- Adult liver transplantation: A UK clinical guideline - part 1: pre-operation.Frontline gastroenterology · 2020Review
- British Society of Gastroenterology (BSG)-led multisociety consensus care bundle for the early clinical management of acute upper gastrointestinal bleeding.Frontline gastroenterology · 2020Article
- How I treat… alcohol-related liver disease.Clinical medicine (London, England) · 2019Review
- Management of decompensated cirrhosis.Clinical medicine (London, England) · 2018Review
- Implementation of a 'care bundle' improves the management of patients admitted to hospital with decompensated cirrhosis.Alimentary pharmacology & therapeutics · 2016Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, there has been a significant increase in the prevalence of chronic liver disease in the UK, and as a result, hospital admissions and deaths due to liver disease have also increased. The 2013 National Confidential Enquiry into Patient Outcome and Death (NCEPOD) of patients with alcohol-related liver disease (ARLD) found that less than half the number of patients who died from ARLD received 'good care', and avoidable deaths were identified. In order to improve the care of patients admitted with ARLD, the NCEPOD report recommended that a 'toolkit' for the acute management of patients admitted with decompensated ARLD be developed and made widely available. As a result, we have developed a 'care bundle' for patients admitted with decompensated cirrhosis (of all aetiologies) to ensure that effective evidence-based treatments are delivered within the first 24 h. This care bundle provides a checklist to ensure that all appropriate investigations are undertaken when a patient with decompensated cirrhosis presents and provides clinicians with clear guidance on the initial management of alcohol withdrawal, infection, acute kidney injury, gastrointestinal bleeding and encephalopathy. The first 24 h are particularly important, as early intervention can reduce mortality and shorten hospital stay, and specialist gastroenterology/liver advice is not always available during this period. This review will discuss the care bundle and the evidence base behind the treatment recommendations made.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.