Evidence map›Paper›PMID 26834698›Full record

ArticleFrontiers in neurology2016

Eye-Movement Training Results in Changes in qEEG and NIH Stroke Scale in Subjects Suffering from Acute Middle Cerebral Artery Ischemic Stroke: A Randomized Control Trial.

Frederick Robert Carrick, Elena Oggero, Guido Pagnacco, Cameron H G Wright, Calixto Machado, Genco Estrada, Alejandro Pando, Juan C Cossio, Carlos Beltrán

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Impact of Early High-protein Diet on Neurofunctional Recovery in Rats with Ischemic Stroke.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Frederick Robert CarrickNeurology, Carrick Institute, Cape Canaveral, FL, USA; Global Clinical Scholars Research Training Program (GCSRT), Harvard Medical School, Boston, MA, USA; Institute of Neurology and Neurosurgery, Havana, Cuba; Bedfordshire Centre for Mental Health Research, University of Cambridge, Cambridge, UK.
Elena OggeroNeurology, Carrick Institute, Cape Canaveral, FL, USA; Electrical and Computer Engineering, University of Wyoming, Laramie, WY, USA.
Guido PagnaccoNeurology, Carrick Institute, Cape Canaveral, FL, USA; Electrical and Computer Engineering, University of Wyoming, Laramie, WY, USA.
Cameron H G WrightNeurology, Carrick Institute, Cape Canaveral, FL, USA; Electrical and Computer Engineering, University of Wyoming, Laramie, WY, USA.
Calixto MachadoNeurology, Carrick Institute, Cape Canaveral, FL, USA; Institute of Neurology and Neurosurgery, Havana, Cuba.
Genco EstradaInstitute of Neurology and Neurosurgery , Havana , Cuba.
Alejandro PandoInstitute of Neurology and Neurosurgery , Havana , Cuba.
Juan C CossioInstitute of Neurology and Neurosurgery , Havana , Cuba.
Carlos BeltránInstitute of Neurology and Neurosurgery , Havana , Cuba.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextEye-movement training (EMT) can induce altered brain activation and change the functionality of saccades with changes of the brain in general.

objectiveTo determine if EMT would result in changes in quantitative electroencephalogram (qEEG) and NIH Stroke Scale (NIHSS) in patients suffering from acute middle cerebral artery (MCA) infarction. Our hypothesis is that there would be positive changes in qEEG and NIHSS after EMT in patients suffering from acute MCA ischemic stroke.

designDouble-blind randomized controlled trial. SETTING AND

participantsThirty-four subjects with acute MCA ischemic stroke treated at university affiliated hospital intensive care unit.

interventionsSubjects were randomized into a "control" group treated only with aspirin (125 mg/day) and a "treatment" group treated with aspirin (125 mg/day) and a subject-specific EMT.

main outcome measuresDelta-alpha ratio, power ratio index, and the brain symmetry index calculated by qEEG and NIHSS.

resultsThere was strong statistical and substantive significant improvement in all outcome measures for the group of stroke patients undergoing EMT. Such improvement was not observed for the "control" group, and there were no adverse effects.

conclusionThe addition of EMT to a MCA ischemic stroke treatment paradigm has demonstrated statistically significant changes in outcome measures and is a low cost, safe, and effective complement to standard treatment.

Indexed as

eye moment therapyischemic strokeNIHSS scoresqEEGsaccadesstroke rehabilitation

Identifiers

PMID26834698
PMCPMC4722822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.