ArticleClinical interventions in aging2016
The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital-based clinical analysis.
Article in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Abnormalities of brain structure and function in cervical spondylosis: a multi-modal voxel-based meta-analysis.Frontiers in neuroscience · 2024Pooled it
- Nondrug therapies for hypertensive patients complicated with cervical spondylosis: A systematic review and meta-analysis.Medicine · 2020Pooled it
- The combined effect of neuro-modulation and neuro-stimulation on pain in patients with cervical radiculopathy - a double-blinded, two-arm parallel randomized controlled trial.The journal of spinal cord medicine · 2025Trial
- Association between the anterior tilt slope and spinal sagittal parameters in asymptomatic adults from Southern China.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Computer-aided diagnosis system for thoracic computed tomography of rib fractures in older emergency patients: A preliminary study.PloS one · 2026Article
- The impact of fall history on instability, disability, and anxiety in patients with chronic neck pain.Turkish journal of medical sciences · 2026Article
- Acupotomy Activates PI3K/Akt Signaling Pathway Mediated by FGF7,10/KDR Axis to Regulate Apoptosis.Journal of pain research · 2026Article
- Observational
- The impact of surgeons' experience and practice on postoperative cervical collar use after single-level anterior cervical discectomy and fusion: a cross-sectional survey in Heilongjiang province, China.BMC musculoskeletal disorders · 2025Article
- Assessing Surgical Outcomes in Cervical Degenerative Disease: The Role of Intraoperative Neurophysiological Monitoring.Journal of clinical medicine · 2025Article
- Unveiling and Validating a Modified Method to Assess Cervical Sagittal Alignment as an Effective Substitute for Conventional C2-7 Cobb Angle.Clinics in orthopedic surgery · 2025Article
- Application of functional magnetic resonance imaging in identifying responsible brain regions associated with spinal diseases related pain.Frontiers in medicine · 2025Article
- Zero-profile implant system versus novel plate systems after ACDF for comparison of sagittal balance parameters and clinical efficacy analysis.Journal of orthopaedic surgery and research · 2024Article
- Early neurological changes in aging cervical spine: insights from PROMIS mobility assessment.GeroScience · 2024Article
- A Comment on 'Musculoskeletal Ultrasound Assessment of the Clinical Efficacy of the Combination of Acupressure and "Three Methods of Neck Movement (TCM)" Therapy in the Treatment of Cervical Spondylosis: A Study Protocol for a Randomized Controlled Trial' [Letter].Journal of pain research · 2024Article
- The imaging of cervical spondylotic myeloradiculopathy.Skeletal radiology · 2023Review
- Article
- Cerebral cortical hemodynamic metrics to aid in assessing pain levels? A pilot study of functional near-infrared spectroscopy.Frontiers in neuroscience · 2023Article
- A skin-integrated device for neck posture monitoring and correction.Microsystems & nanoengineering · 2023Article
- Automated detection of cervical ossification of the posterior longitudinal ligament in plain lateral radiographs of the cervical spine using a convolutional neural network.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeCervical spondylosis is well accepted as a common degenerative change in the cervical spine. Compelling evidence has shown that the incidence of cervical spondylosis increases with age. However, the relationship between age and the incidence of cervical spondylosis remains obscure. It is essential to note the relationship between age and the incidence of cervical spondylosis through more and more clinical data.
methodsIn the case-controlled study reported here, retrospective clinical analysis of 1,276 cases of cervical spondylosis has been conducted. We analyzed the general clinical data, the relationship between age and the incidence of cervical spondylosis, and the relationship between age-related risk factors and the incidence of cervical spondylosis. A chi-square test was used to analyze the associations between different variables. Statistical significance was defined as a P-value of less than 0.05.
resultsThe imaging examination demonstrated the most prominent characteristic features of cervical spondylosis: bulge or herniation at C3-C4, C4-C5, and C5-C6. The incidence of cervical spondylosis increased with aging before age 50 years and decreased with aging after age 50 years, especially in the elderly after 60 years old. The occurrence rate of bulge or herniation at C3-C4, C4-C5, C5-C6, and C6-C7 increased with aging before age 50 years and decreased with aging after age 50 years, especially after 60 years. Moreover, the incidence of hyperosteogeny and spinal stenosis increased with aging before age 60 years and decreased with aging after age 60 years, although there was no obvious change in calcification. The age-related risk factors, such as hypertension, hyperlipidemia, diabetes, cerebral infarct, cardiovascular diseases, smoking, and drinking, have no relationship with the incidence of cervical spondylosis.
conclusionA decreasing proportion of cervical spondylosis with aging occurs in the elderly, while the proportion of cervical spondylosis increases with aging in the young and the adults. This investigation implicates that aging is not only a contributor to the clinical performance of cervical spondylosis in the elderly, although the incidence of cervical spondylosis is proportional to the progress of age.
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