Evidence map›Paper›PMID 26834272›Full record

Trial reportThe Canadian veterinary journal = La revue veterinaire canadienne2016

A novel dextran polymer hydrogel local antimicrobial therapy in dogs: A pilot study.

Travis P Reed, Leslie A Thomas, F Robert Weeren, Jeffrey D Ruth, Brendan B Anders

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in The Canadian veterinary journal = La revue veterinaire canadienne, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Travis P ReedChesapeake Veterinary Surgical Specialists, 1209 Cromwell Bridge Road, Towson, Maryland 21286, USA (Reed, Weeren, Anders); Veterinary Surgical Specialists, 7512 Paula Drive, Tampa, Florida 33615, USA (Thomas); Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, 205 Duck Pond Drive, Blacksburg, Virginia 24061, USA (Ruth).
Leslie A ThomasChesapeake Veterinary Surgical Specialists, 1209 Cromwell Bridge Road, Towson, Maryland 21286, USA (Reed, Weeren, Anders); Veterinary Surgical Specialists, 7512 Paula Drive, Tampa, Florida 33615, USA (Thomas); Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, 205 Duck Pond Drive, Blacksburg, Virginia 24061, USA (Ruth).
F Robert WeerenChesapeake Veterinary Surgical Specialists, 1209 Cromwell Bridge Road, Towson, Maryland 21286, USA (Reed, Weeren, Anders); Veterinary Surgical Specialists, 7512 Paula Drive, Tampa, Florida 33615, USA (Thomas); Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, 205 Duck Pond Drive, Blacksburg, Virginia 24061, USA (Ruth).
Jeffrey D RuthChesapeake Veterinary Surgical Specialists, 1209 Cromwell Bridge Road, Towson, Maryland 21286, USA (Reed, Weeren, Anders); Veterinary Surgical Specialists, 7512 Paula Drive, Tampa, Florida 33615, USA (Thomas); Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, 205 Duck Pond Drive, Blacksburg, Virginia 24061, USA (Ruth).
Brendan B AndersChesapeake Veterinary Surgical Specialists, 1209 Cromwell Bridge Road, Towson, Maryland 21286, USA (Reed, Weeren, Anders); Veterinary Surgical Specialists, 7512 Paula Drive, Tampa, Florida 33615, USA (Thomas); Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, 205 Duck Pond Drive, Blacksburg, Virginia 24061, USA (Ruth).
Virginia–Maryland College of Veterinary Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our purpose was to evaluate physical, laboratory, and/or radiographic abnormalities associated with a novel dextran polymer hydrogel local antimicrobial agent impregnated with amikacin and clindamycin in dogs having tibial plateau leveling osteotomy implants removed due to suspected surgical site infection. A total of 28 client-owned dogs were enrolled and 20 completed the study. Routine plate explantation and bacterial cultures were performed and the polymer hydrogel was applied to the surgery site. No systemic antimicrobials were used after surgery. Serum biochemistry, hematology, urinalysis, physical examinations, and radiographs were monitored before surgery and up to 12 wk after surgery. Sixteen of the 20 dogs (80%) had a positive bacterial culture, 44% of which were methicillin resistant. There were no significant alterations of laboratory values, physical examination, or radiographs to indicate adverse reactions to the polymer hydrogel. There were no signs of inflammation or infection in any patient at the 12-week postoperative recheck.

Indexed as

AmikacinAnimalsAnti-Bacterial AgentsClindamycinDextransDog DiseasesDogsFemaleHydrogelsMalePilot ProjectsSurgical Wound InfectionAmikacinAnti-Bacterial AgentsClindamycinDextransHydrogels

Identifiers

PMID26834272
PMCPMC4713000
OpenAlexW2412003972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.