Evidence map›Paper›PMID 26834185›Full record

Observational studyBritish journal of sports medicine2016

Are there three main subgroups within the patellofemoral pain population? A detailed characterisation study of 127 patients to help develop targeted intervention (TIPPs).

James Selfe, Jessie Janssen, Michael Callaghan, Erik Witvrouw, Chris Sutton, Jim Richards, Maria Stokes, Denis Martin, John Dixon, Russell Hogarth and 4 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in British journal of sports medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04011436 (Therapeutic Effect of Two Muscle Strengthening Programs in Patients With Patellofemoral Pain Syndrome From Bogota, Colombia. Experimental Study, Clinical Controlled Trial), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04011436 nacompletednot on this mapstarted 2018, after this paper: background citation

Therapeutic Effect of Two Muscle Strengthening Programs in Patients With Patellofemoral Pain Syndrome From Bogota, Colombia. Experimental Study, Clinical Controlled Trial

TypeinterventionalSponsorUniversidad Nacional de ColombiaRan2018 to 2019Enrolled40ConditionsPatellofemoral Pain SyndromeArmsStrengthening program
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

James SelfeUniversity of Central Lancashire, Preston, Lancashire, UK.
Jessie JanssenUniversity of Central Lancashire, Preston, Lancashire, UK.
Michael CallaghanInstitute for Inflammation and Repair, Centre for Musculoskeletal Research, University of Manchester, Manchester, UK.
Erik WitvrouwAspetar, Orthopaedic and Sports Medicine Hospital, Doha, Qatar.
Chris SuttonUniversity of Central Lancashire, Preston, Lancashire, UK.
Jim RichardsUniversity of Central Lancashire, Preston, Lancashire, UK.
Maria StokesFaculty of Health Sciences, University of Southampton, Southampton, UK.
Denis MartinTeesside University, Middlesbrough, UK.
John DixonTeesside University, Middlesbrough, UK.
Russell HogarthUniversity of Central Lancashire, Preston, Lancashire, UK.
Vasilios BaltzopoulosBrunel University London, Uxbridge, UK.
Elizabeth RitchieDepartment of Physiotherapy, Harrogate & District NHS Foundation Trust, Harrogate District Hospital, Harrogate, North Yorkshire, UK.
Nigel ArdenUniversity of Oxford, Nuffield Orthopaedic Centre, Oxford, UK.
Paola DeyUniversity of Central Lancashire, Preston, Lancashire, UK.

Funding

Versus Arthritis 19950
6 · The paper itself

Abstract

backgroundCurrent multimodal approaches for the management of non-specific patellofemoral pain are not optimal, however, targeted intervention for subgroups could improve patient outcomes. This study explores whether subgrouping of non-specific patellofemoral pain patients, using a series of low cost simple clinical tests, is possible.

methodThe exclusivity and clinical importance of potential subgroups was assessed by applying à priori test thresholds (1 SD) from seven clinical tests in a sample of adult patients with non-specific patellofemoral pain. Hierarchical clustering and latent profile analysis, were used to gain additional insights into subgroups using data from the same clinical tests.

results130 participants were recruited, 127 had complete data: 84 (66%) female, mean age 26 years (SD 5.7) and mean body mass index 25.4 (SD 5.83), median (IQR) time between onset of pain and assessment was 24 (7-60) months. Potential subgroups defined by the à priori test thresholds were not mutually exclusive and patients frequently fell into multiple subgroups. Using hierarchical clustering and latent profile analysis three subgroups were identified using 6 of the 7 clinical tests. These subgroups were given the following nomenclature: (1) 'strong', (2) 'weak and tighter' and (3) 'weak and pronated foot'.

conclusionsWe conclude that three subgroups of patellofemoral patients may exist based on the results of six clinical tests which are feasible to perform in routine clinical practice. Further research is needed to validate these findings in other data sets and, if supported by external validation, to see if targeted interventions for these subgroups improve patient outcomes.

Indexed as

AdultCluster AnalysisCross-Sectional StudiesFemaleHumansMaleMuscle StrengthPain MeasurementPatellofemoral Pain SyndromePronationRange of Motion, ArticularYoung AdultKneePhysiotherapy

Identifiers

PMID26834185
PMCPMC4975826

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.