ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2016
Genetic dissection of neural circuits underlying sexually dimorphic social behaviours.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 81 citations in OpenAlex.
- Sex-Specific Effects of Hypocretin Receptor Signaling in Corticotropin-Releasing Factor Neurons on Alcohol Drinking, Anxiety, and Extended Amygdala Neuronal Excitability.Biological psychiatry global open science · 2026Article
- Cell Type-Specific Hormonal Signaling Configures Hypothalamic Circuits for Parenting.bioRxiv : the preprint server for biology · 2025Article
- From neurons to novelty: Circuit mechanisms shaping courtship evolution.Current opinion in neurobiology · 2025Review
- Spatiotemporal Patterns of Gene Expression Associated With Mating Stimuli in the Brain of Female Guppies.Genes, brain, and behavior · 2025Article
- Influence of Gonadal and Chromosomal Sex on the Brain Transcriptome in a Mouse Species with Natural Sex Reversal.Molecular biology and evolution · 2025Article
- Sexually Dimorphic Cellular Architecture and Neural Circuity of ovBNST Proenkephalin Neurons.Neuroscience bulletin · 2025Article
- Neuronal Properties in the Lateral Habenula and Adult-Newborn Interactions in Virgin Female and Male Mice.eNeuro · 2025Article
- Sex differences in aggression and its neural substrate in a cichlid fish.Scientific reports · 2025Article
- Role of the bed nucleus of the stria terminalis in feeding.Frontiers in nutrition · 2025Review
- Spatial Single-Cell Mapping of Transcriptional Differences Across Genetic Backgrounds in Mouse Brains.bioRxiv : the preprint server for biology · 2024Article
- Sex-Differential Gene Expression in Developing Human Cortex and Its Intersection With Autism Risk Pathways.Biological psychiatry global open science · 2024Article
- Distributed X chromosome inactivation in brain circuitry is associated with X-linked disease penetrance of behavior.Cell reports · 2024Article
- Sex steroid and cognitive function among community-dwelling older men with or without vascular risk factors: a cross-sectional study.BMC geriatrics · 2024Article
- Sex differences in aggression and its neural substrate in a cichlid fish.bioRxiv : the preprint server for biology · 2024Article
- Androgen receptor deficiency is associated with reduced aromatase expression in the ventromedial hypothalamus of male cichlids.Annals of the New York Academy of Sciences · 2024Article
- Activity of estrogen receptor β expressing neurons in the medial amygdala regulates preference toward receptive females in male mice.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Breaking Through the Bottleneck: Krogh's Principle in Behavioral Neuroendocrinology and the Potential of Gene Editing.Integrative and comparative biology · 2023Review
- Genetic dissection of steroid-hormone modulated social behavior: Novel paralogous genes are a boon for discovery.Hormones and behavior · 2023Review
- The neurophysiological basis of stress and anxiety - comparing neuronal diversity in the bed nucleus of the stria terminalis (BNST) across species.Frontiers in cellular neuroscience · 2023Review
- Male and female mice display consistent lifelong ability to address potential life-threatening cues using different post-threat coping strategies.BMC biology · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The unique hormonal, genetic and epigenetic environments of males and females during development and adulthood shape the neural circuitry of the brain. These differences in neural circuitry result in sex-typical displays of social behaviours such as mating and aggression. Like other neural circuits, those underlying sex-typical social behaviours weave through complex brain regions that control a variety of diverse behaviours. For this reason, the functional dissection of neural circuits underlying sex-typical social behaviours has proved to be difficult. However, molecularly discrete neuronal subpopulations can be identified in the heterogeneous brain regions that control sex-typical social behaviours. In addition, the actions of oestrogens and androgens produce sex differences in gene expression within these brain regions, thereby highlighting the neuronal subpopulations most likely to control sexually dimorphic social behaviours. These conditions permit the implementation of innovative genetic approaches that, in mammals, are most highly advanced in the laboratory mouse. Such approaches have greatly advanced our understanding of the functional significance of sexually dimorphic neural circuits in the brain. In this review, we discuss the neural circuitry of sex-typical social behaviours in mice while highlighting the genetic technical innovations that have advanced the field.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.