Evidence map›Paper›PMID 26833207›Full record

ReviewThe American journal of cardiology2016

Treatment of Massive or Submassive Acute Pulmonary Embolism With Catheter-Directed Thrombolysis.

Ashraf Mostafa, Alexandros Briasoulis, Tesfaye Telila, Kevin Belgrave, Cindy Grines

Abstract readReview
PubMed Publisher
In one paragraph

Review in The American journal of cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. A miraculous recovery:BMJ case reports · 2018
    Article
  12. Article
  13. Review
  14. Article
  15. Predictors of failure and complications of catheter-directed interventions for pulmonary embolism.Journal of vascular surgery. Venous and lymphatic disorders · 2017
    Article
  16. Article
  17. Local Thrombolysis in High-Risk Pulmonary Embolism-13 Years Single-Center Experience.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ashraf MostafaDepartment of Cardiology, Detroit Medical Center, Wayne State University, Detroit, Michigan.
Alexandros BriasoulisDepartment of Cardiology, Detroit Medical Center, Wayne State University, Detroit, Michigan.
Tesfaye TelilaDepartment of Cardiology, Detroit Medical Center, Wayne State University, Detroit, Michigan.
Kevin BelgraveDepartment of Cardiology, Detroit Medical Center, Wayne State University, Detroit, Michigan.
Cindy GrinesDepartment of Cardiology, Detroit Medical Center, Wayne State University, Detroit, Michigan. Electronic address: cgrine@dmc.org.
Wayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presentation of acute pulmonary thromboembolism (PE) can be highly variable resulting in diagnostic challenges and management difficulties. Current guidelines suggest that therapy must be adjusted based on the severity of PE presentation. Systemic thrombolysis is the standard therapy for acute massive PE; however, systemic thrombolysis carries an estimated 20% risk of major hemorrhage, including a 3% to 5% risk of hemorrhagic stroke. There are data supporting the use of catheter-directed therapy (CDT) in massive and submassive PE, but past studies have limited its use to patients in whom systemic thrombolysis has either failed or was contraindicated. There is a paucity of data comparing the efficacy of CDT compared to systemic thrombolysis in different risk groups. This review will summarize the available data on the techniques and indications and outcomes of CDT for acute PE.

Indexed as

CathetersEvidence-Based MedicineFibrinolytic AgentsHumansPractice Guidelines as TopicPulmonary EmbolismRisk FactorsStrokeThrombolytic TherapyTreatment OutcomeUltrasonography, InterventionalFibrinolytic Agents

Identifiers

PMID26833207
OpenAlexW2204732044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.