Evidence map›Paper›PMID 26832887›Full record

ArticleScientific reports2016

Inferring the Dynamics of Effective Population Size Using Autosomal Genomes.

Zheng Hou, Yin Luo, Zhisheng Wang, Hong-Xiang Zheng, Yi Wang, Hang Zhou, Leqin Wu, Li Jin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zheng HouState Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China.
Yin LuoState Key Laboratory of Surface Physics, Key Laboratory for Computational Physical Sciences (Ministry of Education), and Department of Physics, Fudan University, Shanghai, China.
Zhisheng WangSchool of Information Science and Technology, SunYat-sen University, Guangzhou, China.
Hong-Xiang ZhengState Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China.
Yi WangState Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China.
Hang ZhouCAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Leqin WuDepartment of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY, USA.
Li JinState Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China.

Funding

Sex differences in stress-alcohol interactions modulating amygdala activityR00AA021802 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI LOGRIP, MARIAN LEE · 2015 to 2017
$747k
Sex differences in stress-alcohol interactions modulating amygdala activityK99AA021802 · NIAAA · SCRIPPS RESEARCH INSTITUTE, THE · PI LOGRIP, MARIAN LEE · 2013 to 2014
$279k
NIAAA NIH HHS K99 AA021802NIAAA NIH HHS R00 AA021802
6 · The paper itself

Abstract

Next-generation sequencing technology has provided a great opportunity for inferring human demographic history by investigating changes in the effective population size (Ne). In this report, we introduce a strategy for estimating Ne dynamics, allowing the exploration of large multi-locus SNP datasets. We applied this strategy to the Phase 1 Han Chinese samples from the 1000 Genomes Project. The Han Chinese population has undergone a continuous expansion since 25,000 years ago, at first slowly from about 7,300 to 9,800 (at the end of the last glacial maximum about 15,000 YBP), then more quickly to about 46,000 (at the beginning of the Neolithic about 8,000 YBP), and then even more quickly to reach a population size of about 140,000 (recently).

Indexed as

Databases, Nucleic AcidGenome, HumanPolymorphism, Single NucleotidePopulation DynamicsChinaFemaleHumansMale

Identifiers

PMID26832887
PMCPMC4735516

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.