Evidence map›Paper›PMID 26832781›Full record

ArticleClinical oral investigations2016

Zinc-modified nanopolymers improve the quality of resin-dentin bonded interfaces.

Raquel Osorio, Inmaculada Cabello, Antonio L Medina-Castillo, Estrella Osorio, Manuel Toledano

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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  12. [Progress on matrix metalloproteinase inhibitors].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Raquel OsorioDental School, Colegio Maximo, University of Granada, Campus de Cartuja s/n, 18017, Granada, Spain. rosorio@ugr.es.
Inmaculada CabelloDental School, Colegio Maximo, University of Granada, Campus de Cartuja s/n, 18017, Granada, Spain.
Antonio L Medina-CastilloNanoMyP, Spin-Off Enterprise, University of Granada, Edificio BIC-Granada. Av. Innovación1, Armilla, 18016, Granada, Spain.
Estrella OsorioDental School, Colegio Maximo, University of Granada, Campus de Cartuja s/n, 18017, Granada, Spain.
Manuel ToledanoDental School, Colegio Maximo, University of Granada, Campus de Cartuja s/n, 18017, Granada, Spain.
Universidad de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDemineralized collagen fibers at the hybrid layer are susceptible to degradation. Remineralization may aid to improve bond longevity.

objectivesThe aim of the present study was to infiltrate zinc and calcium-loaded polymeric nanoparticles into demineralized dentin to facilitate hybrid layer remineralization. MATERIALS AND

methodsZinc or calcium-loaded polymeric nanoparticles were infiltrated into etched dentin, and Single Bond Adhesive was applied. Bond strength was tested after 24 h and 6 months storage. Nanomechanical properties, dye-assisted confocal laser microscopy, and Masson's trichrome staining evaluation were performed to assess for the hybrid layer morphology, permeability, and remineralization ability after 24 h and 3 months. Data were analyzed by ANOVA and Student-Newman-Keuls multiple comparisons tests (p < 0.05).

resultsImmediate bond strength was not affected by nanoparticles infiltration (25 to 30 MPa), while after 6 months, bond strengths were maintained (22 to 24 MPa). After 3 months, permeability occurred only in specimens in which nanoparticles were not infiltrated. Dentin remineralization, at the bottom of the hybrid layer, was observed in all groups. After microscopy analysis, zinc-loaded nanoparticles were shown to facilitate calcium deposition throughout the entire hybrid layer. Young's modulus at the hybrid layer increased from 2.09 to 3.25 GPa after 3 months, in specimens with zinc nanoparticles; meanwhile, these values were reduced from 1.66 to 0.49 GPa, in the control group.

conclusionInfiltration of polymeric nanoparticles into demineralized dentin increased long-term bond strengths. Zinc-loaded nanoparticles facilitate dentin remineralization within the complete resin-dentin interface. CLINICAL RELEVANCE: Resin-dentin bond longevity and dentin remineralization at the hybrid layer were facilitated by zinc-loaded nanoparticles.

Indexed as

Tooth RemineralizationAcid Etching, DentalCalciumDental BondingDentinDentin-Bonding AgentsElastic ModulusHumansMaterials TestingMicroscopy, ConfocalMolar, ThirdNanoparticlesResin CementsStaining and LabelingSurface PropertiesTensile StrengthCalciumDentin-Bonding AgentsResin CementsZincAdhesivesDentinHybrid layerNanopolymersRemineralizationZinc

Identifiers

PMID26832781
OpenAlexW2254293649

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.