Evidence map›Paper›PMID 26832389›Full record

ArticleJournal of bone and mineral metabolism2017

Vitamin D-binding protein, vitamin D status and serum bioavailable 25(OH)D of young Asian Indian males working in outdoor and indoor environments.

Ravinder Goswami, Soma Saha, Vishnubhatla Sreenivas, Namrata Singh, Ramakrishnan Lakshmy

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In one paragraph

Article in Journal of bone and mineral metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Diabetes mellitus, vitamin D & osteoporosis: Insights.The Indian journal of medical research · 2019
    Article
  11. Review
  12. TheNutrition & metabolism · 2019
    Article
  13. Prevalence of hypovitaminosis D in India & way forward.The Indian journal of medical research · 2018
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Exposure to Sunlight and Vitamin D Synthesis.Indian journal of endocrinology and metabolism
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ravinder GoswamiDepartment of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, 110029, India. gosravinder@hotmail.com.
Soma SahaDepartment of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, 110029, India.
Vishnubhatla SreenivasDepartment of Biostatistics, All India Institute of Medical Sciences, New Delhi, 110029, India.
Namrata SinghDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, 110029, India.
Ramakrishnan LakshmyDepartment of Cardiac Biochemistry, All India Institute of Medical Sciences, New Delhi, 110029, India.
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urban Asian Indians generally have low serum 25(OH)D. Information on serum bioavailable 25(OH)D and the effect of prolonged sun-exposure in them is not known. We assessed serum 25(OH)D and bioavailable 25(OH)D in males with varying durations of sun-exposure in Delhi during August-September. Serum 25(OH)D, vitamin D-binding protein (DBP), bioavailable 25(OH)D, free 25(OH)D index, iPTH, ionized calcium and sun-index were assessed in outdoor, mixed outdoor-indoor and indoor workers (n = 88, 32 and 74, respectively). The mean sun-index (12.0 ± 6.25, 4.3 ± 2.20 and 0.7 ± 0.62, respectively; P < 0.001) was highest outdoors and lowest indoors. Serum 25(OH)D (29.0 ± 8.61, 19.1 ± 5.73 and 10.9 ± 4.19 ng/ml, respectively; P < 0.001), bioavailable 25(OH)D and free 25(OH)D index were maximum in outdoor workers followed by mixed-exposure and indoor workers. Their mean serum DBP levels (241.2 ± 88.77, 239.3 ± 83.40 and 216.6 ± 63.93 µg/ml, respectively; P = 0.12) were comparable. Mean serum iPTH was significantly lower in outdoor than indoor workers and showed inverse correlations with serum 25(OH)D, bioavailable 25(OH)D and free 25(OH)D index (r = -0.401, -0.269 and -0.236, respectively; P < 0.001 in all). Daily dietary-calorie intake was higher and calcium lower in outdoor than indoor workers. On regression analysis, sun-exposure was the only significant variable, increasing serum 25(OH)D by 2.03 ng/ml per hour of sun-exposure (95 % confidence interval 1.77-2.28; P < 0.001). Outdoor workers with prolonged sun-exposure were vitamin D-sufficient, with higher serum bioavailable 25(OH)D than the indoor workers during summer. Use of serum DBP levels did not affect the interpretation of their vitamin D status.

Indexed as

SunlightWorkplaceAdultCalcium, DietaryHumansIndiaMaleParathyroid HormoneSeasonsVitamin DVitamin D-Binding ProteinWhite PeopleYoung AdultCalcium, DietaryParathyroid HormoneVitamin DVitamin D-Binding ProteinAsian IndiansBioavailable 25(OH)DSerum 25(OH)DSun-exposureVitamin D-binding protein

Identifiers

PMID26832389
OpenAlexW2260718217

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.