SynthesisBMC musculoskeletal disorders2016
Does exchange arthroplasty of an infected shoulder prosthesis provide better eradication rate and better functional outcome, compared to a permanent spacer or resection arthroplasty? a systematic review.
Synthesis in BMC musculoskeletal disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- One- and two-stage surgical revision of infected shoulder prostheses following arthroplasty surgery: A systematic review and meta-analysis.Scientific reports · 2019Pooled it
- Does cemented or cementless single-stage exchange arthroplasty of chronic periprosthetic hip infections provide similar infection rates to a two-stage? A systematic review.BMC infectious diseases · 2016Pooled it
- Management of shoulder prosthetic joint infections with humeral bone loss using a customizable articulating long stem spacer (The Frankenspacer).JSES reviews, reports, and techniques · 2025Article
- Management of periprosthetic joint infection of the shoulder: A narrative review.Journal of clinical orthopaedics and trauma · 2024Article
- High infection control rate after systematic one-stage procedure for shoulder arthroplasty chronic infection.International orthopaedics · 2023Article
- Preventing and Treating Infection in Reverse Total Shoulder Arthroplasty.Current reviews in musculoskeletal medicine · 2023Review
- Changes in microbiological spectrum and antibiotic susceptibility in two-stage exchange for periprosthetic shoulder infections.Archives of orthopaedic and trauma surgery · 2023Article
- Patient-specific articulating spacer for two-stage shoulder arthroplasty exchange.Operative Orthopadie und Traumatologie · 2023Article
- Prosthetic joint infections of the shoulder: A review of the recent literature.Journal of orthopaedics · 2023Article
- Comparison of surgical treatment options in periprosthetic shoulder infections: a systematic review from 2016 to 2022.Annals of joint · 2023Review
- Two-Stage Exchange Arthroplasty for Periprosthetic Shoulder Infection Is Associated with High Rate of Failure to Reimplant and Mortality.Journal of clinical medicine · 2021Article
- Clinical Outcome of Two-Stage Revision after Periprosthetic Shoulder Infection.Journal of clinical medicine · 2021Article
- Failed Reverse Shoulder Arthroplasty and Recommendations for Revision.Current reviews in musculoskeletal medicine · 2020Review
- Conservative management of chronicJSES open access · 2019Article
- Scoping review: Diagnosis and management of periprosthetic joint infection in shoulder arthroplasty.Shoulder & elbow · 2019Article
- Implant Removal and Spacer Placement for Infected Shoulder Arthroplasty: Risk Factors for Repeat Procedures, Spacer Retention, and Mortality.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2018Article
- Results of cement spacer sonication in the second stage of two-stage treatment of shoulder arthroplasty infection.Journal of orthopaedic surgery and research · 2018Observational
- Staged Revision With Antibiotic Spacers for Shoulder Prosthetic Joint Infections Yields High Infection Control.Clinical orthopaedics and related research · 2018Article
- Periprosthetic Joint Infection of Shoulder Arthroplasties: Diagnostic and Treatment Options.BioMed research international · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe best surgical modality for treating chronic periprosthetic shoulder infections has not been established, with a lack of randomised comparative studies. This systematic review compares the infection eradication rate and functional outcomes after single- or two-stage shoulder exchange arthroplasty, to permanent spacer implant or resection arthroplasty.
methodsFull-text papers and those with an abstract in English published from January 2000 to June 2014, identified through international databases, such as EMBASE and PubMed, were reviewed. Those reporting the success rate of infection eradication after a single-stage exchange, two-stage exchange, resection arthroplasty or permanent spacer implant, with a minimum follow-up of 6 months and sample size of 5 patients were included.
resultsEight original articles reporting the results after resection arthroplasty (n = 83), 6 on single-stage exchange (n = 75), 13 on two-stage exchange (n = 142) and 8 papers on permanent spacer (n = 68) were included. The average infection eradication rate was 86.7 % at a mean follow-up of 39.8 months (SD 20.8) after resection arthroplasty, 94.7 % at 46.8 months (SD 17.6) after a single-stage exchange, 90.8 % at 37.9 months (SD 12.8) after two-stage exchange, and 95.6 % at 31.0 months (SD 9.8) following a permanent spacer implant. The difference was not statistically significant (p = 0.650). Regarding functional outcome, patients treated with single-stage exchange had statistically significant better postoperative Constant scores (mean 51, SD 13) than patients undergoing a two-stage exchange (mean 44, SD 9), resection arthroplasty (mean 32, SD 7) or a permanent spacer implant (mean 31, SD 9) (p = 0.029). However, when considering studies comparing pre- and post-operative Constant scores, the difference was not statistically significant.
conclusionThis systematic review failed to demonstrate a clear difference in infection eradication and functional improvement between all four treatment modalities for established periprosthetic shoulder infection. The relatively low number of patients and the methodological limitations of the studies available point out the need for well designed multi-center trials to further assess the best treatment option of peri-prosthetic shoulder infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.