ArticleOptics express2016
Interferometric Near-Infrared Spectroscopy (iNIRS) for determination of optical and dynamical properties of turbid media.
Article in Optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 46 citations in OpenAlex.
- Compact FPGA-based software correlator for real-time blood flow measurement with diffuse correlation spectroscopy.Biomedical optics express · 2026Article
- Monte Carlo simulations of time-resolved blood flow index: times-of-flight beyond ∼1 ns are necessary for brain-dominated measurements.Neurophotonics · 2026Article
- CoMind R1: a time-resolved interferometric optical neuromonitoring system for pulsatile cerebral blood flow measurement at late times-of-flight.Neurophotonics · 2026Article
- Comparative validation of speckle contrast optical spectroscopy against diffuse correlation spectroscopy for monitoring human cerebral blood flow.Neurophotonics · 2026Article
- 1060 nm interferometric near-infrared spectroscopy.Optics letters · 2025Article
- Study of Time-Resolved Dynamics in Turbid Medium Using a Single-Cavity Dual-Comb Laser.ACS photonics · 2024Article
- Interferometric near-infrared spectroscopy (iNIRS) reveals that blood flow index depends on wavelength.Biomedical optics express · 2024Article
- Diffuse Correlation Spectroscopy: A Review of Recent Advances in Parallelisation and Depth Discrimination Techniques.Sensors (Basel, Switzerland) · 2023Review
- Recovering fetal signals transabdominally through interferometric near-infrared spectroscopy (iNIRS).Biomedical optics express · 2023Article
- Experimental demonstration of a new near-infrared spectroscopy technique based on optical dual-comb: DC-NIRS.Scientific reports · 2023Article
- Massively parallel, real-time multispeckle diffuse correlation spectroscopy using a 500 × 500 SPAD camera.Biomedical optics express · 2023Article
- Interferometric diffusing wave spectroscopy imaging with an electronically variable time-of-flight filter.Optica · 2023Article
- Interferometric diffuse optics: recent advances and future outlook.Neurophotonics · 2023Article
- Diffuse correlation spectroscopy: current status and future outlook.Neurophotonics · 2023Article
- Continuous-wave parallel interferometric near-infrared spectroscopy (CWBiomedical optics express · 2022Article
- Quantifying the Cerebral Hemometabolic Response to Blood Transfusion in Pediatric Sickle Cell Disease With Diffuse Optical Spectroscopies.Frontiers in neurology · 2022Article
- Scanning interferometric near-infrared spectroscopy.Optics letters · 2022Article
- Time-domain diffuse correlation spectroscopy (TD-DCS) for noninvasive, depth-dependent blood flow quantification in human tissue in vivo.Scientific reports · 2021Article
- Time-of-flight resolved light field fluctuations reveal deep human tissue physiology.Nature communications · 2020Article
- Correlation gating quantifies the optical properties of dynamic media in transmission.Optics letters · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
We introduce and implement interferometric near-infrared spectroscopy (iNIRS), which simultaneously extracts optical and dynamical properties of turbid media through analysis of a spectral interference fringe pattern. The spectral interference fringe pattern is measured using a Mach-Zehnder interferometer with a frequency-swept narrow linewidth laser. Fourier analysis of the detected signal is used to determine time-of-flight (TOF)-resolved intensity, which is then analyzed over time to yield TOF-resolved intensity autocorrelations. This approach enables quantification of optical properties, which is not possible in conventional, continuous-wave near-infrared spectroscopy (NIRS). Furthermore, iNIRS quantifies scatterer motion based on TOF-resolved autocorrelations, which is a feature inaccessible by well-established diffuse correlation spectroscopy (DCS) techniques. We prove this by determining TOF-resolved intensity and temporal autocorrelations for light transmitted through diffusive fluid phantoms with optical thicknesses of up to 55 reduced mean free paths (approximately 120 scattering events). The TOF-resolved intensity is used to determine optical properties with time-resolved diffusion theory, while the TOF-resolved intensity autocorrelations are used to determine dynamics with diffusing wave spectroscopy. iNIRS advances the capabilities of diffuse optical methods and is suitable for in vivo tissue characterization. Moreover, iNIRS combines NIRS and DCS capabilities into a single modality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.