Evidence map›Paper›PMID 26831364›Full record

ArticleThe International journal on drug policy2016

"Can't you initiate me here?": Challenges to timely initiation on antiretroviral therapy among methadone clients in Dar es Salaam, Tanzania.

Haneefa T Saleem, Dorothy Mushi, Saria Hassan, R Douglas Bruce, Alexis Cooke, Jessie Mbwambo, Barrot H Lambdin

Abstract read
In one paragraph

Article in The International journal on drug policy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haneefa T SaleemPangaea Global AIDS, 436, 14th Street, Suite 920, Oakland, CA 94612, United States. Electronic address: hsaleem1@jhu.edu.
Dorothy MushiMuhimbili University of Health and Allied Sciences, Department of Psychiatry, P.O. Box 65293, Dar es Salaam, Tanzania.
Saria HassanPangaea Global AIDS, 436, 14th Street, Suite 920, Oakland, CA 94612, United States.
R Douglas BrucePangaea Global AIDS, 436, 14th Street, Suite 920, Oakland, CA 94612, United States; Cornell Scott-Hill Health Center, 428 Columbus Avenue, New Haven, CT 06519, United States; Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, United States.
Alexis CookeUniversity of California, Los Angeles, Fielding School of Public Health, Department of Community Health Sciences, United States.
Jessie MbwamboMuhimbili University of Health and Allied Sciences, Department of Psychiatry, P.O. Box 65293, Dar es Salaam, Tanzania.
Barrot H LambdinRTI International, 351 California Street, Suite 500, San Francisco, CA 94104, United States; University of California San Francisco, San Francisco, CA, United States; University of Washington, Seattle, WA, United States.

Funding

Reducing Failure-to-Initiate ART among People Who Inject Drugs: the IMAT StrategyR34DA037787 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI LAMBDIN, BARROT HOPKINS · 2014 to 2016
$585k
NIDA NIH HHS 1R34DA037787NIDA NIH HHS R34 DA037787
6 · The paper itself

Abstract

backgroundDespite dramatic improvement in antiretroviral therapy (ART) access globally, people living with HIV who inject drugs continue to face barriers that limit their access to treatment. This paper explores barriers and facilitators to ART initiation among clients attending a methadone clinic in Dar es Salaam, Tanzania.

methodsWe interviewed 12 providers and 20 clients living with HIV at the Muhimbili National Hospital methadone clinic between January and February 2015. We purposively sampled clients based on sex and ART status and providers based on job function. To analyze interview transcripts, we adopted a content analysis approach.

resultsParticipants identified several factors that hindered timely ART initiation for clients at the methadone clinic. These included delays in CD4 testing and receiving CD4 test results; off-site HIV clinics; stigma operating at the individual, social and institutional levels; insufficient knowledge of the benefits of early ART initiation among clients; treatment breakdown at the clinic level possibly due to limited staff; and initiating ART only once one feels physically ill. Participants perceived social support as a buffer against stigma and facilitator of HIV treatment. Some clients also reported that persistent monitoring and follow-up on their HIV care and treatment by methadone clinic providers led them to initiate ART.

conclusionHealth system factors, stigma and limited social support pose challenges for methadone clients living with HIV to initiate ART. Our findings suggest that on-site point-of-care CD4 testing, a peer support system, and trained HIV treatment specialists who are able to counsel HIV-positive clients and initiate them on ART at the methadone clinic could help reduce barriers to timely ART initiation for methadone clients.

Indexed as

Health Services AccessibilityAnti-HIV AgentsCD4 Lymphocyte CountFemaleHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansInterviews as TopicMaleMethadoneOpiate Substitution TreatmentPoint-of-Care SystemsSocial StigmaSocial SupportTanzaniaTime FactorsAnti-HIV AgentsMethadoneAntiretroviral therapyIntegrated servicesMethadoneQualitativeTanzania

Identifiers

PMID26831364
PMCPMC4829458

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.