Trial reportBMC neurology2016
Antioxidant activity of linalool in patients with carpal tunnel syndrome.
Trial report in BMC neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 90 citations in OpenAlex.
- From Tradition to Bioactivity: Chemical and Biological Evaluation of a Reformulated Algerian Ancestral Soap Enriched With Lavandula dentata L. Essential Oil.Chemistry & biodiversity · 2026Article
- Antioxidative and anti-inflammatory effects of monoterpene linalool in rats with letrozole-induced polycystic ovarian syndrome: modulation of autophagy and apoptosis.Inflammopharmacology · 2026Article
- Genetic potential of Limosilactobacillus fermentum 5.1.2 produces metabolite compounds with antioxidant activity.Archives of microbiology · 2026Article
- Comparative Profiling and In Silico Multitarget Analysis of Volatile Constituents fromPlants (Basel, Switzerland) · 2026Article
- Phytochemical Characterization and Potential Anti-Oxidative Activity of Lavandula angustifolia subsp. pyrenaica (DC.), Lavandula x intermedia Emeric ex Loisel cv Grosso, and cv Super Essential Oils Compared to a Commercial Lavender Essential Oil.Chemistry & biodiversity · 2025Article
- Linalool and Geraniol Defend Neurons from Oxidative Stress, Inflammation, and Iron Accumulation in In Vitro Parkinson's Models.Antioxidants (Basel, Switzerland) · 2024Article
- Metabolic profiling and enzyme inhibitory activity of the essential oil of citrus aurantium fruit peel.BMC complementary medicine and therapies · 2024Article
- Inhalation ofPharmaceuticals (Basel, Switzerland) · 2023Article
- Chemical Composition of theAntibiotics (Basel, Switzerland) · 2023Article
- Phytochemical characterization, antioxidant activity and antihypertensive evaluation ofHeliyon · 2023Article
- Chemical Profiles, In Vitro Antioxidant and Antifungal Activity of Four DifferentMolecules (Basel, Switzerland) · 2023Article
- Chemical Characterization, Antioxidant, Antimicrobial, and Antibiofilm Activities of Essential Oils ofBiochemistry research international · 2023Article
- Phytochemistry, Bioactivities and Traditional Uses ofMolecules (Basel, Switzerland) · 2022Review
- Chemometric Analysis Based on GC-MS Chemical Profiles of ThreePlants (Basel, Switzerland) · 2022Article
- Biphasic effect of the dietary phytochemical linalool on angiogenesis and metastasis.Molecular and cellular biochemistry · 2022Article
- Preparation of an Antimicrobial and Antioxidant Bio-Polymer Film and Its Application as Glazing Shell for Postharvest Quality of Fresh-Cut Apple.Foods (Basel, Switzerland) · 2022Article
- Anti-Diabetes, Anti-Gout, and Anti-Leukemia Properties of Essential Oils from Natural SpicesMolecules (Basel, Switzerland) · 2022Article
- Linalool as a Therapeutic and Medicinal Tool in Depression Treatment: A Review.Current neuropharmacology · 2022Review
- Composition and pharmacological activity of essential oils from two importedJournal of Taibah University Medical Sciences · 2021Article
- Linalool Alleviates AOxidative medicine and cellular longevity · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCarpal tunnel syndrome (CTS) is a common peripheral neuropathy and ischemic-reperfusion injury. Oxidative stress is considered a major cause of CTS. Linalool, a component of essential oils, has antioxidant activity. This study was designed to determine the effects of linalool inhalation on oxidative stress in patients with CTS.
methodsThis double-blind, placebo-controlled study assessed the effects of linalool inhalation on oxidative stress in patients with CTS. Thirty-seven subjects, with and without CTS, were randomized to inhalation of 1% linalool or carrier oil. 1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, systolic blood pressure (sBP), diastolic blood pressure (dBP) and pulse rate were analyzed.
resultsDPPH inhibition was significantly higher in both experimental groups than in their respective controls. Moreover inhalation of linalool reduced sBP, dBP and pulse rate in the CTS group, and pulse rate in the non-CTS group. However, there were no significant differences among the study groups in nitrite levels, sBP, dBP and pulse rate.
conclusionsInhalation of linalool increases antioxidative activity and reduces blood pressure and pulse rate in patients with CTS.
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