SynthesisJournal of general internal medicine2016
Benefits and Harms of Screening Mammography by Comorbidity and Age: A Qualitative Synthesis of Observational Studies and Decision Analyses.
Synthesis in Journal of general internal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- The influence of multi-morbidities on colorectal cancer screening recommendations and completion.Cancer causes & control : CCC · 2021Trial
- Breast cancer screening in women aged 75 and older: Insights from an aging region in Japan.Preventive medicine reports · 2025Article
- Breast cancer screening motivation and behaviours of women aged over 75 years: a scoping review.BMC women's health · 2024Article
- Clinician and patient perspectives on screening mammography among women age 75 and older: A pilot study of a novel decision aid.PEC innovation · 2023Article
- Current Challenges and Perspectives in Breast Cancer in Elderly Women: The Senologic International Society (SIS) Survey.European journal of breast health · 2023Article
- "It's something I'll do until I die": A qualitative examination into why older women in the U.S. continue screening mammography.Cancer medicine · 2022Article
- Stage IV Non-breast Cancer Patients and Screening Mammography: It is Time to Stop.Annals of surgical oncology · 2022Article
- Moderation effect of mammography screening among women with multiple chronic conditions.Scientific reports · 2022Article
- Mammography adherence in relation to function-related indicators in older women.Preventive medicine · 2022Article
- A mixed-methods study of multi-level factors influencing mammography overuse among an older ethnically diverse screening population: implications for de-implementation.Implementation science communications · 2021Article
- Impact of Screening on Breast Cancer Incidence in Kazakhstan: Results of Component Analysis.Asian Pacific journal of cancer prevention : APJCP · 2021Article
- Function-related Indicators and Outcomes of Screening Mammography in Older Women: Evidence from the Breast Cancer Surveillance Consortium Cohort.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021Article
- Screening Mammography Outcomes: Risk of Breast Cancer and Mortality by Comorbidity Score and Age.Journal of the National Cancer Institute · 2020Article
- Older breast cancer undertreatment: unconscious bias to undertreat-potential role for the international geriatric radiotherapy group?Translational cancer research · 2020Review
- Optimizing selection of candidates for lung cancer screening: role of comorbidity, frailty and life expectancy.Translational lung cancer research · 2019Article
- Screening mammography among nursing home residents in the United States: Current guidelines and practice.Journal of geriatric oncology · 2018Article
- Article
- Utilization of screening mammography in older women according to comorbidity and age: protocol for a systematic review.Systematic reviews · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveWe conducted a systematic review to assess the quality and limitations of published studies examining benefits and harms of screening mammography in relation to comorbidity and age.
methodsWe searched MEDLINE and EMBASE from January 1980 through June 2013 for studies that examined benefits or harms of screening mammography in women aged 65 years or older in relation to comorbidity. For each study, we extracted data regarding setting, design, quality, screening schedule, measure of comorbidity, and estimates of benefits and/or harms. We reviewed 1760 titles, identifying 7 articles that met the inclusion criteria: prospective cohort (two studies), retrospective cohort (two studies), and decision analyses (three studies). No randomized controlled trials were identified.
resultsAt least one measure of life expectancy or reduction in the risk of breast cancer death as a marker of benefit was examined in four studies, whereas three studies addressed the harms of screening mammography, including false-positive results. Both cohort studies and decision analyses showed that screening benefits decreased with increasing age and comorbidity burden.
conclusionsThe limited evidence currently available suggests that, apart from older women with severe comorbidity, women 65 and older may experience improvements in life expectancy from screening. Given the potential for harm, it is unclear whether the magnitude of the benefit is sufficient to warrant regular screening. Women, clinicians and policymakers should consider these factors in deciding whether continue screening.
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