Evidence map›Paper›PMID 26830208›Full record

ArticleGenetics, selection, evolution : GSE2016

Genomic prediction of breeding values for carcass traits in Nellore cattle.

Gerardo A Fernandes Júnior, Guilherme J M Rosa, Bruno D Valente, Roberto Carvalheiro, Fernando Baldi, Diogo A Garcia, Daniel G M Gordo, Rafael Espigolan, Luciana Takada, Rafael L Tonussi and 5 more

Abstract read
In one paragraph

Article in Genetics, selection, evolution : GSE, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Gerardo A Fernandes JúniorFaculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-900, Brazil. gerardojjunior@yahoo.com.br.
Guilherme J M RosaDepartment of Animal Sciences, University of Wisconsin-Madison, Madison, WI, 53706, USA. grosa@wisc.edu.
Bruno D ValenteDepartment of Animal Sciences, University of Wisconsin-Madison, Madison, WI, 53706, USA. bvalente@wisc.edu.
Roberto CarvalheiroFaculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-900, Brazil. rcar@fcav.unesp.br.
Fernando BaldiFaculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-900, Brazil. fernandobaldiuy@gmail.com.
Diogo A GarciaFaculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-900, Brazil. diogo.garcia@brf-br.com.
Daniel G M GordoFaculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-900, Brazil. danielmansangordo@gmail.com.
Rafael EspigolanFaculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-900, Brazil. espigolan@yahoo.com.br.
Luciana TakadaFaculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-900, Brazil. lutakada@gmail.com.
Rafael L TonussiFaculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-900, Brazil. rafaeltonussi@yahoo.com.br.
Willian B F de AndradeFaculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-900, Brazil. willb.galena@yahoo.com.br.
Ana F B MagalhãesFaculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-900, Brazil. anafabriciabm@yahoo.com.br.
Luis A L CharduloFaculdade de Medicina Veterinária e Zootecnia, UNESP, Botucatu, SP, 18618-970, Brazil. lachard@ibb.unesp.br.
Humberto TonhatiFaculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-900, Brazil. tonhati@fcav.unesp.br.
Lucia G de AlbuquerqueFaculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-900, Brazil. lgalb@fcav.unesp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of this study was to evaluate the accuracy of genomic predictions for rib eye area (REA), backfat thickness (BFT), and hot carcass weight (HCW) in Nellore beef cattle from Brazilian commercial herds using different prediction models.

methodsPhenotypic data from 1756 Nellore steers from ten commercial herds in Brazil were used. Animals were offspring of 294 sires and 1546 dams, reared on pasture, feedlot finished, and slaughtered at approximately 2 years of age. All animals were genotyped using a 777k Illumina Bovine HD SNP chip. Accuracy of genomic predictions of breeding values was evaluated by using a 5-fold cross-validation scheme and considering three models: Bayesian ridge regression (BRR), Bayes C (BC) and Bayesian Lasso (BL), and two types of response variables: traditional estimated breeding value (EBV), and phenotype adjusted for fixed effects (Y*).

resultsThe prediction accuracies achieved with the BRR model were equal to 0.25 (BFT), 0.33 (HCW) and 0.36 (REA) when EBV was used as response variable, and 0.21 (BFT), 0.37 (HCW) and 0.46 (REA) when using Y*. Results obtained with the BC and BL models were similar. Accuracies increased for traits with a higher heritability, and using Y* instead of EBV as response variable resulted in higher accuracy when heritability was higher.

conclusionsOur results indicate that the accuracy of genomic prediction of carcass traits in Nellore cattle is moderate to high. Prediction of genomic breeding values from adjusted phenotypes Y* was more accurate than from EBV, especially for highly heritable traits. The three models considered (BRR, BC and BL) led to similar predictive abilities and, thus, either one could be used to implement genomic prediction for carcass traits in Nellore cattle.

Indexed as

Models, GeneticQuantitative Trait, HeritableRed MeatSelective BreedingAnimalsBayes TheoremBrazilCattleGenomicsGenotypeMalePhenotypePolymorphism, Single Nucleotide

Identifiers

PMID26830208
PMCPMC4734869

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.