Evidence map›Paper›PMID 26830005›Full record

ArticleNature communications2016

Phylogenomic and biogeographic reconstruction of the Trichinella complex.

Pasi K Korhonen, Edoardo Pozio, Giuseppe La Rosa, Bill C H Chang, Anson V Koehler, Eric P Hoberg, Peter R Boag, Patrick Tan, Aaron R Jex, Andreas Hofmann and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 145 citations in OpenAlex.

  1. Ancient and current association of theJournal of virology · 2026
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  6. Evolution of sensory systems underlies the emergence of predatory feeding behaviors in nematodes.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  8. First assessment of the prevalence ofThe veterinary quarterly · 2025
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  10. Genetic structure ofInternational journal for parasitology. Parasites and wildlife · 2025
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  12. Over a century of progress onFood and waterborne parasitology · 2024
    Review
  13. Enhanced Genomic and Transcriptomic Resources forInternational journal of molecular sciences · 2024
    Article
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  16. Italian journal of food safety · 2023
    Article
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  18. Large-scale proteomic analysis ofFrontiers in parasitology · 2023
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  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 4 countries.

Pasi K KorhonenFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Edoardo PozioIstituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Giuseppe La RosaIstituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Bill C H ChangFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Anson V KoehlerFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Eric P HobergUnited States National Parasite Collection, US Department of Agriculture, Agricultural Research Service, Beltsville, Maryland 20705, USA.
Peter R BoagDepartment of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.
Patrick TanGenome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Republic of Singapore.
Aaron R JexFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Andreas HofmannFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, Victoria 3010, Australia.ORCID http://orcid.org/0000-0003-4408-5467
Paul W SternbergDivision of Biology, Howard Hughes Medical Institute, California Institute of Technology, Pasadena, California 91125, USA.ORCID http://orcid.org/0000-0002-7699-0173
Neil D YoungFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Robin B GasserFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, Victoria 3010, Australia.
The University of Melbourne · AUIstituto Superiore di Sanità · ITAgricultural Research Service · USCalifornia Institute of Technology · USDuke-NUS Medical School · SGGriffith University · AUMonash University · AU

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Trichinellosis is a globally important food-borne parasitic disease of humans caused by roundworms of the Trichinella complex. Extensive biological diversity is reflected in substantial ecological and genetic variability within and among Trichinella taxa, and major controversy surrounds the systematics of this complex. Here we report the sequencing and assembly of 16 draft genomes representing all 12 recognized Trichinella species and genotypes, define protein-coding gene sets and assess genetic differences among these taxa. Using thousands of shared single-copy orthologous gene sequences, we fully reconstruct, for the first time, a phylogeny and biogeography for the Trichinella complex, and show that encapsulated and non-encapsulated Trichinella taxa diverged from their most recent common ancestor ∼21 million years ago (mya), with taxon diversifications commencing ∼10-7 mya.

Indexed as

GenomicsPhylogenyAnimalsGene Expression RegulationGenome, HelminthGenotypeTrichinella

Identifiers

PMID26830005
PMCPMC4740406
OpenAlexW2258527837

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.