ReviewCurrent heart failure reports2016
Comorbidities in Heart Failure: Are There Gender Differences?
Review in Current heart failure reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 49 citations in OpenAlex.
- Sex-Based Differences in Management and Outcomes of Patients Admitted or Transferred to Advanced Therapy Centers for Heart Failure.Journal of clinical medicine · 2026Article
- Trends and Disparities inGastroenterology research and practice · 2026Article
- Sex and Gender Aspects in New-Onset Heart Failure Prognosis: A Review of Recent Advances.Current heart failure reports · 2025Review
- Females and Exercise Capacity Impairment in Heart Failure: A Sex-Focused Analysis.Journal of cardiovascular development and disease · 2025Article
- Are There Gender Differences in the Benefits of Multidisciplinary Care in Patients with Heart Failure? Results from the UMIPIC Program.Journal of clinical medicine · 2025Article
- Development a nomogram prognostic model for survival in heart failure patients based on the HF-ACTION data.BMC medical informatics and decision making · 2024Article
- Sex- and Gender-Based Analysis on Norepinephrine Use in Septic Shock: Why Is It Still a Male World?Microorganisms · 2024Article
- Sex Differences in Circulating Biomarkers of Heart Failure.Current heart failure reports · 2024Review
- The Association Between Intra-abdominal Pressure and Diuretic Response in Heart Failure.Current heart failure reports · 2023Review
- Sex differences in cardiovascular outcomes of SGLT-2 inhibitors in heart failure randomized controlled trials: A systematic review and meta-analysis.American heart journal plus : cardiology research and practice · 2023Article
- Trends and Disparities in Outcomes ofJournal of clinical medicine research · 2022Article
- Trends in survival of Swedish men and women with heart failure from 1987 to 2014: a population-based case-control study.ESC heart failure · 2022Article
- Beta-Blocker Use in Older Hospitalized Patients Affected by Heart Failure and Chronic Obstructive Pulmonary Disease: An Italian Survey From the REPOSI Register.Frontiers in cardiovascular medicine · 2022Article
- Impact of sex differences in co-morbidities and medication adherence on outcome in 25 776 heart failure patients.ESC heart failure · 2021Article
- Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart.Cardiovascular research · 2021Review
- The Female Sex Confers Different Prognosis in Heart Failure: Same Mortality but More Readmissions.Frontiers in cardiovascular medicine · 2021Article
- Article
- Cardiogenic Shock Clinical Presentation, Management, and In-Hospital Outcomes in Patients Admitted to the Acute Cardiac Care Unit of a Tertiary Hospital: Does Gender Play a Role?Journal of clinical medicine · 2020Article
- Care Dependency in Patients with Heart Failure: A Cross-Sectional Study in Spain.International journal of environmental research and public health · 2020Article
- PATTERN OF ANAEMIA AND ITS CORRELATES IN NIGERIANS WITH HEART FAILURE.Annals of Ibadan postgraduate medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
Abstract
Compared to men, women with heart failure (HF) are often older, smoke less, and have more preserved ejection fraction (EF) and hypertensive HF rather than HF of ischemic etiology. Gender-stratified outcomes on comorbidities data in HF are scarce. Women have traditionally been underrepresented in HF trials. Although data suggest that overall prognosis may be better in women, they experience lower quality of life with greater functional impairment from HF compared to men. Gender differences have been reported for comorbid diabetes, chronic obstructive pulmonary disease, renal dysfunction, anemia, and depression and may explain gender disparity in outcomes. However, possible confounding of comorbidities with known prognostic determinants in HF (such as EF) as well as gender differences in the utilization of medical therapies obscures interpretation. In this review, we will explore the evidence for gender differences in non-cardiovascular comorbidities in HF. Our findings may guide clinicians to individualize HF care, according to best practice, in the hope of improving prognosis for this chronic and debilitating condition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.