ArticleScientific reports2016
Green synthesis of silver nanoparticles and characterization of their inhibitory effects on AGEs formation using biophysical techniques.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.
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Who cites it
93 citing papers in PubMed, 387 citations in OpenAlex.
- Exploring the bioactive potential of green synthesized silver nanoparticles coated serratiopeptidase and chalcone derivatives.Discover nano · 2026Article
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- Green synthesis of silver nanoparticles withRSC advances · 2026Article
- Phytochemical insights and green synthesis of silver nanoparticles using Maytenus gracilipes, with evaluation of their antibacterial activity.BMC complementary medicine and therapies · 2026Article
- Synergistic Antibacterial Effects of Photosensitizing Silver Nanoparticles Synthesized fromJournal of lasers in medical sciences · 2026Article
- Diosmin-Capped Silver Nanoparticles Promote Osteogenic Differentiation of Human Periodontal Ligament Stem Cells: Box-Behnken Optimization and in vitro Evaluation.International journal of nanomedicine · 2026Article
- Eco-friendly synthesis and biomedical potential of silver nanoparticles using Pandanus dubius extract.Scientific reports · 2025Article
- Biosynthesized Silver Nanoparticles Modulate Inflammation in a Palatine Wound Model.Clinical and experimental dental research · 2025Article
- Characterization and Performance Evaluation of Cotton Fabrics Functionalized via In Situ Green Synthesis of Silver Nanoparticles UsingPolymers · 2025Article
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- Biodegradable chitosan/PVA-based hydrogel incorporating green synthesized silver nanoparticles for wound healing applications.BMC chemistry · 2025Article
- Deposition of Ag/TMC Nanoparticles via MAPLE to Enhance the Mechanical and Antimicrobial Properties of Silicone Hydrogel.ACS omega · 2025Article
- Silver Nanoparticles (AgNPs) as Potential Antiviral Agents: Synthesis, Biophysical Properties, Safety, Challenges and Future Directions─Update Review.Molecules (Basel, Switzerland) · 2025Review
- Investigation of Cell Damage Induced by Silver Nanoparticles in a Model Cell System.Pharmaceutics · 2025Article
- Inhibition effect of AGEs formationFrontiers in nutrition · 2025Article
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- Green-synthesized silver nanoparticles fromHeliyon · 2024Article
- Nanotherapy for Cancer and Biological Activities of Green Synthesized AgNPs Using AqueousPharmaceuticals (Basel, Switzerland) · 2024Article
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- Experimental and theoretical validation for transmutation of palladium at electrochemical interfaces.Scientific reports · 2024Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advanced glycation end-products (AGEs) resulting from non-enzymatic glycation are one of the major factors implicated in secondary complications of diabetes. Scientists are focusing on discovering new compounds that may be used as potential AGEs inhibitors without affecting the normal structure and function of biomolecules. A number of natural and synthetic compounds have been proposed as AGE inhibitors. In this study, we investigated the inhibitory effects of AgNPs (silver nanoparticles) in AGEs formation. AgNPs (~30.5 nm) synthesized from Aloe Vera leaf extract were characterized using UV-Vis spectroscopy, energy-dispersive X-ray spectroscopy (EDX), high resolution-transmission electron microscopy, X-ray diffraction and dynamic light scattering (DLS) techniques. The inhibitory effects of AgNPs on AGEs formation were evaluated by investigating the degree of reactivity of free amino groups (lysine and arginine residues), protein-bound carbonyl and carboxymethyl lysine (CML) content, and the effects on protein structure using various physicochemical techniques. The results showed that AgNPs significantly inhibit AGEs formation in a concentration dependent manner and that AgNPs have a positive effect on protein structure. These findings strongly suggest that AgNPs may play a therapeutic role in diabetes-related complications.
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