Evidence map›Paper›PMID 26829772›Full record

ArticleIEEE transactions on bio-medical engineering2016

Iterative Covariance-Based Removal of Time-Synchronous Artifacts: Application to Gastrointestinal Electrical Recordings.

Jonathan C Erickson, Joy Putney, Douglas Hilbert, Niranchan Paskaranandavadivel, Leo K Cheng, Greg O'Grady, Timothy R Angeli

Abstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonathan C EricksonDepartment of Physics and Engineering, Washington and Lee University, Lexington, VA, USA.
Joy PutneyDepartment of Physics and Engineering, Washington and Lee University.
Douglas HilbertDepartments of Mathematics and Biochemistry, Washington and Lee University.
Niranchan PaskaranandavadivelAuckland Bioengineering InstituteUniversity of Auckland.
Leo K ChengAuckland Bioengineering Institute.
Greg O'GradyAuckland Bioengineering Institute.
Timothy R AngeliAuckland Bioengineering InstituteUniversity of Auckland.

Funding

Realistic models of gastrointestinal bioelectromagnetismR01DK064775 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CHENG, LEO · 2004 to 2014
$2.6M
NIDDK NIH HHS R01 DK064775
6 · The paper itself

Abstract

objectiveThe aim of this study was to develop, validate, and apply a fully automated method for reducing large temporally synchronous artifacts present in electrical recordings made from the gastrointestinal (GI) serosa, which are problematic for properly assessing slow wave dynamics. Such artifacts routinely arise in experimental and clinical settings from motion, switching behavior of medical instruments, or electrode array manipulation.

methodsA novel iterative Covariance-Based Reduction of Artifacts (COBRA) algorithm sequentially reduced artifact waveforms using an updating across-channel median as a noise template, scaled and subtracted from each channel based on their covariance.

resultsApplication of COBRA substantially increased the signal-to-artifact ratio (12.8 ± 2.5 dB), while minimally attenuating the energy of the underlying source signal by 7.9% on average ( -11.1 ± 3.9 dB).

conclusionCOBRA was shown to be highly effective for aiding recovery and accurate marking of slow wave events (sensitivity = 0.90 ± 0.04; positive-predictive value = 0.74 ± 0.08) from large segments of in vivo porcine GI electrical mapping data that would otherwise be lost due to a broad range of contaminating artifact waveforms. SIGNIFICANCE: Strongly reducing artifacts with COBRA ultimately allowed for rapid production of accurate isochronal activation maps detailing the dynamics of slow wave propagation in the porcine intestine. Such mapping studies can help characterize differences between normal and dysrhythmic events, which have been associated with GI abnormalities, such as intestinal ischemia and gastroparesis. The COBRA method may be generally applicable for removing temporally synchronous artifacts in other biosignal processing domains.

Indexed as

AlgorithmsArtifactsSignal Processing, Computer-AssistedAnimalsDatabases, FactualElectrophysiologyJejunumReproducibility of ResultsSwine

Identifiers

PMID26829772
PMCPMC5094763

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.