Evidence map›Paper›PMID 26829523›Full record

ArticleRadiology2016

Thickness of the Meniscal Lamellar Layer: Correlation with Indentation Stiffness and Comparison of Normal and Abnormally Thick Layers by Using Multiparametric Ultrashort Echo Time MR Imaging.

Ja-Young Choi, Reni Biswas, Won C Bae, Robert Healey, Michael Im, Sheronda Statum, Eric Y Chang, Jiang Du, Graeme M Bydder, Darryl D'Lima and 1 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ja-Young ChoiFrom the Department of Radiology, Seoul National University Hospital, Seoul, Korea (J.Y.C.); Department of Radiology, University of California-San Diego Medical Center, 3350 La Jolla Village Dr, Mail Code 8226, San Diego, CA 92103 (R.B., W.C.B., M.I., S.S., E.Y.C., J.D., G.M.B., C.B.C.); Department of Orthopedic Surgery, University of California, La Jolla, Calif (R.H.); Radiology Service, Veterans Administration San Diego Healthcare System, La Jolla, Calif (E.Y.C., C.B.C.); and Molecular and Experimental Medicine, Scripps Translational Science Institute, La Jolla, Calif (D.D.).
Reni BiswasFrom the Department of Radiology, Seoul National University Hospital, Seoul, Korea (J.Y.C.); Department of Radiology, University of California-San Diego Medical Center, 3350 La Jolla Village Dr, Mail Code 8226, San Diego, CA 92103 (R.B., W.C.B., M.I., S.S., E.Y.C., J.D., G.M.B., C.B.C.); Department of Orthopedic Surgery, University of California, La Jolla, Calif (R.H.); Radiology Service, Veterans Administration San Diego Healthcare System, La Jolla, Calif (E.Y.C., C.B.C.); and Molecular and Experimental Medicine, Scripps Translational Science Institute, La Jolla, Calif (D.D.).
Won C BaeFrom the Department of Radiology, Seoul National University Hospital, Seoul, Korea (J.Y.C.); Department of Radiology, University of California-San Diego Medical Center, 3350 La Jolla Village Dr, Mail Code 8226, San Diego, CA 92103 (R.B., W.C.B., M.I., S.S., E.Y.C., J.D., G.M.B., C.B.C.); Department of Orthopedic Surgery, University of California, La Jolla, Calif (R.H.); Radiology Service, Veterans Administration San Diego Healthcare System, La Jolla, Calif (E.Y.C., C.B.C.); and Molecular and Experimental Medicine, Scripps Translational Science Institute, La Jolla, Calif (D.D.).
Robert HealeyFrom the Department of Radiology, Seoul National University Hospital, Seoul, Korea (J.Y.C.); Department of Radiology, University of California-San Diego Medical Center, 3350 La Jolla Village Dr, Mail Code 8226, San Diego, CA 92103 (R.B., W.C.B., M.I., S.S., E.Y.C., J.D., G.M.B., C.B.C.); Department of Orthopedic Surgery, University of California, La Jolla, Calif (R.H.); Radiology Service, Veterans Administration San Diego Healthcare System, La Jolla, Calif (E.Y.C., C.B.C.); and Molecular and Experimental Medicine, Scripps Translational Science Institute, La Jolla, Calif (D.D.).
Michael ImFrom the Department of Radiology, Seoul National University Hospital, Seoul, Korea (J.Y.C.); Department of Radiology, University of California-San Diego Medical Center, 3350 La Jolla Village Dr, Mail Code 8226, San Diego, CA 92103 (R.B., W.C.B., M.I., S.S., E.Y.C., J.D., G.M.B., C.B.C.); Department of Orthopedic Surgery, University of California, La Jolla, Calif (R.H.); Radiology Service, Veterans Administration San Diego Healthcare System, La Jolla, Calif (E.Y.C., C.B.C.); and Molecular and Experimental Medicine, Scripps Translational Science Institute, La Jolla, Calif (D.D.).
Sheronda StatumFrom the Department of Radiology, Seoul National University Hospital, Seoul, Korea (J.Y.C.); Department of Radiology, University of California-San Diego Medical Center, 3350 La Jolla Village Dr, Mail Code 8226, San Diego, CA 92103 (R.B., W.C.B., M.I., S.S., E.Y.C., J.D., G.M.B., C.B.C.); Department of Orthopedic Surgery, University of California, La Jolla, Calif (R.H.); Radiology Service, Veterans Administration San Diego Healthcare System, La Jolla, Calif (E.Y.C., C.B.C.); and Molecular and Experimental Medicine, Scripps Translational Science Institute, La Jolla, Calif (D.D.).
Eric Y ChangFrom the Department of Radiology, Seoul National University Hospital, Seoul, Korea (J.Y.C.); Department of Radiology, University of California-San Diego Medical Center, 3350 La Jolla Village Dr, Mail Code 8226, San Diego, CA 92103 (R.B., W.C.B., M.I., S.S., E.Y.C., J.D., G.M.B., C.B.C.); Department of Orthopedic Surgery, University of California, La Jolla, Calif (R.H.); Radiology Service, Veterans Administration San Diego Healthcare System, La Jolla, Calif (E.Y.C., C.B.C.); and Molecular and Experimental Medicine, Scripps Translational Science Institute, La Jolla, Calif (D.D.).
Jiang DuFrom the Department of Radiology, Seoul National University Hospital, Seoul, Korea (J.Y.C.); Department of Radiology, University of California-San Diego Medical Center, 3350 La Jolla Village Dr, Mail Code 8226, San Diego, CA 92103 (R.B., W.C.B., M.I., S.S., E.Y.C., J.D., G.M.B., C.B.C.); Department of Orthopedic Surgery, University of California, La Jolla, Calif (R.H.); Radiology Service, Veterans Administration San Diego Healthcare System, La Jolla, Calif (E.Y.C., C.B.C.); and Molecular and Experimental Medicine, Scripps Translational Science Institute, La Jolla, Calif (D.D.).
Graeme M BydderFrom the Department of Radiology, Seoul National University Hospital, Seoul, Korea (J.Y.C.); Department of Radiology, University of California-San Diego Medical Center, 3350 La Jolla Village Dr, Mail Code 8226, San Diego, CA 92103 (R.B., W.C.B., M.I., S.S., E.Y.C., J.D., G.M.B., C.B.C.); Department of Orthopedic Surgery, University of California, La Jolla, Calif (R.H.); Radiology Service, Veterans Administration San Diego Healthcare System, La Jolla, Calif (E.Y.C., C.B.C.); and Molecular and Experimental Medicine, Scripps Translational Science Institute, La Jolla, Calif (D.D.).
Darryl D'LimaFrom the Department of Radiology, Seoul National University Hospital, Seoul, Korea (J.Y.C.); Department of Radiology, University of California-San Diego Medical Center, 3350 La Jolla Village Dr, Mail Code 8226, San Diego, CA 92103 (R.B., W.C.B., M.I., S.S., E.Y.C., J.D., G.M.B., C.B.C.); Department of Orthopedic Surgery, University of California, La Jolla, Calif (R.H.); Radiology Service, Veterans Administration San Diego Healthcare System, La Jolla, Calif (E.Y.C., C.B.C.); and Molecular and Experimental Medicine, Scripps Translational Science Institute, La Jolla, Calif (D.D.).
Christine B ChungFrom the Department of Radiology, Seoul National University Hospital, Seoul, Korea (J.Y.C.); Department of Radiology, University of California-San Diego Medical Center, 3350 La Jolla Village Dr, Mail Code 8226, San Diego, CA 92103 (R.B., W.C.B., M.I., S.S., E.Y.C., J.D., G.M.B., C.B.C.); Department of Orthopedic Surgery, University of California, La Jolla, Calif (R.H.); Radiology Service, Veterans Administration San Diego Healthcare System, La Jolla, Calif (E.Y.C., C.B.C.); and Molecular and Experimental Medicine, Scripps Translational Science Institute, La Jolla, Calif (D.D.).

Funding

UTE MRI of Tissue Response in Meniscal RepairR01AR064321 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHUNG, CHRISTINE B · 2014 to 2018
$2.3M
Non-invasive Morphologic and Biochemical Assessment of Tendon with Novel UTE-MRIIK2CX000749 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2012 to 2015
–
CSRD VA IK2 CX000749NIAMS NIH HHS R01 AR064321
6 · The paper itself

Abstract

Purpose To determine the relationship between lamellar layer thickness on ultrashort echo time (UTE) magnetic resonance (MR) images and indentation stiffness of human menisci and to compare quantitative MR imaging values between two groups with normal and abnormally thick lamellar layers. Materials and Methods This was a HIPAA-compliant, institutional review board-approved study. Nine meniscal pieces were obtained from seven donors without gross meniscal pathologic results (mean age, 57.4 years ± 14.5 [standard deviation]). UTE MR imaging and T2, UTE T2*, and UTE T1ρ mapping were performed. The presence of abnormal lamellar layer thickening was determined and thicknesses were measured. Indentation testing was performed. Correlation between the thickness and indentation stiffness was assessed, and mean quantitative MR imaging values were compared between the groups. Results Thirteen normal lamellar layers had mean thickness of 232 μm ± 85 and indentation peak force of 1.37 g ± 0.87. Four abnormally thick lamellar layers showed mean thickness of 353.14 μm ± 98.36 and peak force 0.72 g ± 0.31. In most cases, normal thicknesses showed highly positive correlation with the indentation peak force (r = 0.493-0.912; P < .001 to .05). However, the thickness in two abnormal lamellar layers showed highly negative correlation (r = -0.90, P < .001; and r = -0.23, P = .042) and no significant correlation in the others. T2, UTE T2*, and UTE T1ρ values in abnormally thick lamellar layers were increased compared with values in normal lamellar layers, although only the UTE T2* value showed significant difference (P = .010). Conclusion Variation of lamellar layer thickness in normal human menisci was evident on two-dimensional UTE images. In normal lamellar layers, thickness is highly and positively correlated with surface indentation stiffness. UTE T2* values may be used to differentiate between normal and abnormally thickened lamellar layers. (©) RSNA, 2016.

Indexed as

Biomechanical PhenomenaCadaverFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMeniscusMiddle Aged

Identifiers

PMID26829523
PMCPMC4942992

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