ReviewJournal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer2016
Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?
Abstract readReview
In one paragraph
Review in Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed, 3 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
110 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Prevalence of TP-53/Rb-1 Co-Mutation in Large Cell Neuroendocrine Carcinoma.Frontiers in oncology · 2021Pooled it
- Correlation between adverse events after drug treatment and theThe Journal of international medical research · 2019Pooled it
- Trial
- Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2019Trial
- Multicenter, Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Pravastatin Added to First-Line Standard Chemotherapy in Small-Cell Lung Cancer (LUNGSTAR).Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017Trial
- Reprogramming resistance in advanced lung cancer: epigenetic modulation to restore therapeutic vulnerability.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Review
- FOXA1 drives chemoresistance through activating Wnt pathway in small cell lung cancer.Translational lung cancer research · 2026Article
- NFIB Regulates Chemoresistance in Small Cell Lung Cancer by Suppressing Notch Signaling Activity.Cancer reports (Hoboken, N.J.) · 2026Article
- Actin dysregulation induces neuroendocrine plasticity and immune evasion: a vulnerability of small cell lung cancer.Nature communications · 2025Article
- Interpretable multiclassification machine learning models in predicting the extent of small cell lung cancer metastasis.Scientific reports · 2025Article
- Phase I Dose-Escalation Results for the Delta-Like Ligand 3/CD3 IgG-Like T-Cell Engager Obrixtamig (BI 764532) in Patients With Delta-Like Ligand 3+ Small Cell Lung Cancer or Neuroendocrine Carcinomas.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025Article
- Functional characterization of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer.Cell reports · 2025Article
- Predicting survival in small cell lung cancer patients undergoing various treatments: a machine learning approach.Translational lung cancer research · 2025Article
- Current and future perspectives in extensive-stage small-cell lung cancer.Therapeutic advances in medical oncology · 2025Review
- HPN328, a Trispecific T Cell-Activating Protein Construct Targeting DLL3-Expressing Solid Tumors.Molecular cancer therapeutics · 2024Article
- MYC Family Amplification Dictates Sensitivity to BET Bromodomain Protein Inhibitor Mivebresib (ABBV075) in Small-Cell Lung Cancer.Molecular cancer research : MCR · 2024Article
- Functional Characterisation of the ATOH1 Molecular Subtype Indicates a Pro-Metastatic Role in Small Cell Lung Cancer.bioRxiv : the preprint server for biology · 2024Article
- Hippocampal protection during preventive cranial irradiation and neurocognitive functions in patients with small cell lung cancer.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024Article
- Novel Therapeutic Options for Small Cell Lung Cancer.Current oncology reports · 2023Review
50 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
54 authors.
Paul A BunnUniversity of Colorado Cancer Center, Aurora, Colorado.
John D MinnaUniversity of Texas Southwestern Medical Center, Dallas, Texas.
Alexander AugustynUniversity of Texas Southwestern Medical Center, Dallas, Texas.
Adi F GazdarUniversity of Texas Southwestern Medical Center, Dallas, Texas.
Youcef OuadahStanford University, Stanford, California.
Mark A KrasnowStanford University, Stanford, California.
Anton BernsNetherlands Cancer Institute, Amsterdam, The Netherlands.
Elisabeth BrambillaGrenoble University Hospital Center, Grenoble, France.
Natasha RekhtmanMemorial Sloan Kettering Cancer Center, New York, New York.
Pierre P MassionVanderbilt University, Nashville, Tennessee.
Matthew NiederstMassachusetts General Hospital, Boston, Massachusetts.
Martin PeiferUniversity of Cologne, Cologne, Germany.
Jun YokotaInstitute of Predictive and Personalized Medicine of Cancer, Barcelona, Spain; National Cancer Center Research Institute, Tokyo, Japan.
Ramaswamy GovindanWashington University, St. Louis, Missouri.
John T PoirierMemorial Sloan Kettering Cancer Center, New York, New York.
Lauren A ByersUniversity of Texas MD Anderson Cancer Center, Houston, Texas.
Murry W WynesInternational Association for the Study of Lung Cancer, Aurora, Colorado.
David G McFaddenUniversity of Texas Southwestern Medical Center, Dallas, Texas.
David MacPhersonFred Hutchinson Cancer Research Center, Seattle, Washington.
Christine L HannJohns Hopkins School of Medicine, Baltimore, Maryland.
Anna F FaragoMassachusetts General Hospital, Boston, Massachusetts.
Caroline DiveCancer Research UK Manchester Institute, Manchester, United Kingdom.
Beverly A TeicherNational Cancer Institute, Bethesda, Maryland.
Craig D PeacockCleveland Clinic, Cleveland, Ohio.
Jane E JohnsonUniversity of Texas Southwestern Medical Center, Dallas, Texas.
Melanie H CobbUniversity of Texas Southwestern Medical Center, Dallas, Texas.
Hans-Guido WendelMemorial Sloan Kettering Cancer Center, New York, New York.
David SpigelSara Cannon Research Institute, Nashville, Tennessee.
Julien SageStanford University, Stanford, California.
Ping YangMayo Clinic Cancer Center, Rochester, Minnesota.
M Catherine PietanzaMemorial Sloan Kettering Cancer Center, New York, New York.
Lee M KrugMemorial Sloan Kettering Cancer Center, New York, New York.
John HeymachUniversity of Texas MD Anderson Cancer Center, Houston, Texas.
Peter UjhazyMayo Clinic Cancer Center, Rochester, Minnesota.
Caicun ZhouCancer Institute of Tongji University Medical School, Shanghai, China.
Koichi GotoNational Cancer Center Hospital East, Chiba, Japan.
Afshin DowlatiCase Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio.
Camilla Laulund ChristensenDana-Farber Cancer Institute, Boston, Massachusetts.
Keunchil ParkSamsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Lawrence H EinhornIndiana University, Indianapolis, Indiana.
Martin J EdelmanUniversity of Maryland, Greenebaum Cancer Center, Baltimore, Maryland.
Giuseppe GiacconeGeorgetown University, Washington, District of Columbia.
David E GerberUniversity of Texas Southwestern Medical Center, Dallas, Texas.
Ravi SalgiaUniversity of Chicago, Chicago, Illinois.
Taofeek OwonikokoEmory University, Atlanta, Georgia.
Shakun MalikNational Cancer Institute, Bethesda, Maryland.
Niki KarachaliouQuiron Dexeus University Hospital, Barcelona, Spain.
David R GandaraUniversity of California Davis Comprehensive Cancer Center, Davis, California.
Ben J SlotmanVrije Universiteit Medical Center, Amsterdam, Netherlands.
Fiona BlackhallUniversity Manchester, Manchester, United Kingdom.
Glenwood GossUniversity of Ottawa, Ottawa, Canada.
Roman ThomasUniversity of Cologne, Cologne, Germany.
Charles M RudinMemorial Sloan Kettering Cancer Center, New York, New York.
Fred R HirschUniversity of Colorado Cancer Center, Aurora, Colorado. Electronic address: Fred.Hirsch@ucdenver.edu.
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MUNIVERSITY OF TEXAS--SPORE IN LUNG CANCERP50CA070907 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI HEYMACH, JOHN V., MINNA, JOHN D. · 1996 to 2024
$57.4MTissue Bank and Biomarkers CoreP50CA058187 · NCI · UNIVERSITY OF COLORADO DENVER · PI NEMENOFF, RAPHAEL A. · 1992 to 2018
$43.8MLeveraging innovative technologies in basic and clinical cancer researchT32CA009302 · NCI · STANFORD UNIVERSITY · PI LAURA D ATTARDI, Aaron M Newman · 1985 to 2026
$19.1MDana Farber/Harvard Cancer Consortium Career Development Program in Clinical OncologyK12CA087723 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI David Tsai Ting · 2002 to 2026
$17.9MDefining a Molecularly Distinct Subtype of Non Small Cell Lung CancerF30CA168264 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI AUGUSTYN, ALEXANDER · 2013 to 2016
$100kCancer Research UK 19278Cancer Research UK 20465NCI NIH HHS F30 CA168264NCI NIH HHS K12 CA087723NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA058187NCI NIH HHS P50 CA070907NCI NIH HHS T32 CA009302
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsHumansLung NeoplasmsMolecular BiologySmall Cell Lung CarcinomaGene mutationsImmunotherapyNeuroendocrineSmall cell lung cancerTherapy
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