ReviewInternational journal of environmental research and public health2016
Biomarker-Based Approaches for Assessing Alcohol Use Disorders.
Review in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 120 citations in OpenAlex.
- Phosphatidylethanol in Comparison to Self-Reported Alcohol Consumption Among HIV-Infected Women in a Randomized Controlled Trial of Naltrexone for Reducing Hazardous Drinking.Alcoholism, clinical and experimental research · 2018Trial
- Socioeconomic Status, Alcohol Use, and Mortality: Results From a Prospective Cohort Study.Alcohol, clinical & experimental research · 2026Article
- Helicobacter pylori infection and liver function alterations in individuals undergoing gastric cancer screening: a cohort study.Scientific reports · 2026Article
- The effects of alcohol dependence on the CSF proteome in mice: Evidence for blood-brain barrier dysfunction and neuroinflammation.Neurobiology of disease · 2026Article
- PEth Cut-Off Thresholds for Hazardous Alcohol Consumption Based on a Drinking Study.Drug testing and analysis · 2026Article
- Lab tests can be used to predict phosphatidylethanol-measured high-risk alcohol use among people with HIV: a proof-of-concept using machine learning.Alcohol and alcoholism (Oxford, Oxfordshire) · 2025Article
- The effects of Alcohol Dependence on the CSF Proteome in Mice: Evidence for Blood-Brain Barrier Dysfunction and Neuroinflammation.bioRxiv : the preprint server for biology · 2025Article
- Does the Interaction Between Alcohol Use and Depression Exacerbate Hyperglycemia Risk? A Cross-Sectional Study Beyond Additive Effects.Medicina (Kaunas, Lithuania) · 2025Article
- Imaging of Microtubules in a Nonhuman Primate Model of Alcohol Use Disorder.ACS pharmacology & translational science · 2025Article
- AUDIT C compared to PEth in middle-aged volunteers.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024Article
- Mental Manifestations and Biomarkers of Alcohol Consumption.Life (Basel, Switzerland) · 2024Review
- Inflammation, Immunonutritive, and Cardiovascular Risk Biomarkers in Men With Alcohol Use Disorder.Cureus · 2024Article
- Article
- Narrowing the Patient-Physician Gap Based on Self-Reporting and Monthly Hepatologist Feedback for Patients With Alcohol-Related Liver Disease: Interventional Pilot Study Using a Journaling Smartphone App.JMIR formative research · 2023Article
- Biomarkers of alcohol abuse potentially predict delirium, delirium duration and mortality in critically ill patients.iScience · 2023Article
- Impact of Physical Activity on the Characteristics and Metabolic Consequences of Alcohol Consumption: A Cross-Sectional Population-Based Study.International journal of environmental research and public health · 2022Article
- Phosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of Differences Between Alcohol-Related and Non-Alcohol-Related Cirrhosis Candidates.Annals of transplantation · 2022Article
- Alcohol Consumption and Its Influence on the Clinical Picture of Puumala Hantavirus Infection.Viruses · 2022Article
- Changes in SerumBiomolecules · 2022Article
- Heavy episodic drinking and HIV disclosure by HIV treatment status among People with HIV in IeDEA Cameroon.The International journal on drug policy · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although alcohol use disorders rank among the leading public health problems worldwide, hazardous drinking practices and associated morbidity continue to remain underdiagnosed. It is postulated here that a more systematic use of biomarkers improves the detection of the specific role of alcohol abuse behind poor health. Interventions should be initiated by obtaining information on the actual amounts of recent alcohol consumption through questionnaires and measurements of ethanol and its specific metabolites, such as ethyl glucuronide. Carbohydrate-deficient transferrin is a valuable tool for assessing chronic heavy drinking. Activities of common liver enzymes can be used for screening ethanol-induced liver dysfunction and to provide information on the risk of co-morbidities including insulin resistance, metabolic syndrome and vascular diseases. Conventional biomarkers supplemented with indices of immune activation and fibrogenesis can help to assess the severity and prognosis of ethanol-induced tissue damage. Many ethanol-sensitive biomarkers respond to the status of oxidative stress, and their levels are modulated by factors of life style, including weight gain, physical exercise or coffee consumption in an age- and gender-dependent manner. Therefore, further attention should be paid to defining safe limits of ethanol intake in various demographic categories and establishing common reference intervals for biomarkers of alcohol use disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.