ArticleMedicina oral, patologia oral y cirugia bucal2016
Clinical findings and risk factors to oral squamous cell carcinoma in young patients: A 12-year retrospective analysis.
Article in Medicina oral, patologia oral y cirugia bucal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Pectoralis major myocutaneous versus pectoralis major myofascial flap for type III and type IV tongue defects reconstruction in patients operated for squamous cell carcinoma: A protocol.Bioinformation · 2026Article
- Tongue cancer in pregnancy: challenges and outcomes. A case series and review of the literature.Oral and maxillofacial surgery · 2025Review
- Comparing clinicopathological profile and treatment outcomes in younger versus older patients with carcinoma oral tongue - a retrospective cohort study.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025Article
- Molecular Targets of Plant-Derived Bioactive Compounds in Oral Squamous Cell Carcinoma.Cancers · 2024Review
- Update on Prevalence of Pain in Patients with Cancer 2022: A Systematic Literature Review and Meta-Analysis.Cancers · 2023Review
- Chemopreventive and Anticancer Role of Resveratrol against Oral Squamous Cell Carcinoma.Pharmaceutics · 2023Review
- Article
- Evaluation of Risk Factors in Patients with Head and Neck Cancer: A Case Control Study.Addiction & health · 2023Article
- Immunoexpression of p53 mutant-type in Iranian patients with primary and recurrence oral squamous cell carcinoma.European journal of translational myology · 2022Article
- Clinicopathological characteristics predicting advanced stage and surgical margin invasion of oral squamous cell carcinoma: A single-center study on 10 years of cancer registry data.Oncology letters · 2022Article
- Using Next-Generation Sequencing and Bioinformatic Methods to Predict New Genes That May Be Regulated by CD47 in Oral Squamous Cell Carcinoma.Current issues in molecular biology · 2022Article
- Construction of prognostic signature of patients with oral squamous cell carcinoma based on pyroptosis-related long non-coding RNAs.Frontiers in surgery · 2022Article
- Clinicopathologic Characteristics of Young Patients with Oral Squamous Cell Carcinoma.Head and neck pathology · 2021Article
- Socioeconomic indicators and economic investments influence oral cancer mortality in Latin America.BMC public health · 2021Article
- Trend of hospitalized cases of oral cancer in Brazil and its relationship with oral health coverage in public health system between 2009 and 2017.Medicina oral, patologia oral y cirugia bucal · 2021Article
- Systematic Review: Cardiac Metastasis of Lingual Squamous Cell Carcinoma.Spartan medical research journal · 2021Article
- Binge drinking, HIV/HPV co-infection risk, and HIV testing: Factors associated with HPV vaccination among young adults in the United States.Preventive medicine · 2020Article
- Head and neck squamous cell carcinoma in young patients: a 26-year clinicopathologic retrospective study in a Brazilian specialized center.Medicina oral, patologia oral y cirugia bucal · 2020Article
- Comparison of Squamous Cell Carcinoma of the Tongue between Young and Old Patients.Journal of pathology and translational medicine · 2019Article
- Identification of Novel MicroRNAs and Their Diagnostic and Prognostic Significance in Oral Cancer.Cancers · 2019Article
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7 authors.
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Abstract
backgroundIn recent years have been observed an increased incidence of OSCC in young individuals. Based on this, the aim this study was to describe the clinical characteristics of all cases of OSCC in younger patients, diagnosed in two oncology referral hospitals, at the northeast region of Brazil within a 12-year period. MATERIAL AND
methodsData regarding general characteristics of patients (age, gender and tobacco and/or alcohol habits) and information about the lesions (tumor location, size, regional lymph node metastasis, distant metastasis and clinical stage) were submitted to descriptive and inferential analysis. Statistical analysis included Chi-square and Fisher's exact tests (P<0.05).
resultsOut of 2311 registered cases of OSCC, 76 (3.3%) corresponded to OSCC in patients under 45 years old. Most of them were male (n=62, 81.6%) and tobacco and/or alcohol users (n=40, 52.8%). The most frequent site was the tongue (n=31, 40.8%), with predominance of cases classified at advanced clinical stage (III and IV, n = 46, 60.5%). The advanced stage of OSCC (III and IV) was statistically associated with male gender (P=0.035), lower education level (P=0.007), intraoral sites (P<0.001), presence of pain symptomatology (P=0.006), and consumption of tobacco and/or alcohol (P=0.001).
conclusionsThe profile of OSCC in young patients resembles to the commonly characteristics reported for overall population. The late diagnosis in young patients usually results in poor prognosis, associated with gender, harmful habits and tumor location. Although prevalence is low, stimulus to prevention and to early diagnosis should be addressed to young individuals exposed to risk factors.
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