Evidence map›Paper›PMID 26826894›Full record

ArticleJournal of electrocardiology

Quantitative Assessment of Vectorcardiographic Loop Morphology.

Golriz Sedaghat, Elyar Ghafoori, Jonathan W Waks, Muammar M Kabir, Alexei Shvilkin, Mark E Josephson, Larisa G Tereshchenko

Abstract read
In one paragraph

Article in Journal of electrocardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Golriz SedaghatKnight Cardiovascular Institute, Oregon Health & Science University, Portland, OR; Portland State University, Portland, OR.
Elyar GhafooriKnight Cardiovascular Institute, Oregon Health & Science University, Portland, OR; University of Utah, Salt Lake City, UT.
Jonathan W WaksDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Muammar M KabirKnight Cardiovascular Institute, Oregon Health & Science University, Portland, OR.
Alexei ShvilkinDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Mark E JosephsonDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Larisa G TereshchenkoKnight Cardiovascular Institute, Oregon Health & Science University, Portland, OR. Electronic address: tereshch@ohsu.edu.

Funding

Novel ECG Measures and Risk of Sudden Cardiac DeathR01HL118277 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TERESHCHENKO, LARISA GENNADIEVNA · 2013 to 2016
$1.5M
NHLBI NIH HHS 1R01HL118277NHLBI NIH HHS R01 HL118277
6 · The paper itself

Abstract

Vectorcardiography (VCG), developed 100years ago, characterizes clinically important electrophysiological properties of the heart. In this study, VCG QRS loop roundness, planarity, thickness, rotational angle, and dihedral angle were measured in 81 healthy control subjects (39.0±14.2y; 51.8% male; 94% white), and 8 patients with infarct-cardiomyopathy and sustained monomorphic ventricular tachycardia (VT) (68.0±7.8y, 37.5% male). The angle between two consecutive QRS vectors was defined as the rotational angle, while dihedral angle quantified planar alteration over the QRS loop. In VT subjects, planarity index decreased (0.63±0.22 vs. 0.88±0.10; P=0.014), and dihedral angle was significantly more variable (variance of dihedral angle, median (IQR): 897(575-1450) vs. 542(343-773); P=0.029; rMSSD: 47.7±12.7 vs. 35.1±13.1; P=0.027). Abnormal electrophysiological substrate in VT patients is characterized by the appearance of QRS loop folding, likely due to local conduction block. The presence of fragmented QRS complexes on the 12-lead ECG had low sensitivity (31%) for detecting QRS loop folding on the VCG.

Indexed as

AlgorithmsAdultAgedComputer SimulationDiagnosis, Computer-AssistedDiagnosis, DifferentialFemaleHumansMaleModels, StatisticalMyocardial InfarctionReproducibility of ResultsSensitivity and SpecificityTachycardia, VentricularVectorcardiographyPlanarityVectorcardiographyVentricular tachycardia

Identifiers

PMID26826894
PMCPMC4775292

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.