Evidence map›Paper›PMID 26826748›Full record

ArticleOphthalmology2016

Uncorrected Hyperopia and Preschool Early Literacy: Results of the Vision in Preschoolers-Hyperopia in Preschoolers (VIP-HIP) Study.

VIP-HIP Study Group, Marjean Taylor Kulp, Elise Ciner, Maureen Maguire, Bruce Moore, Jill Pentimonti, Maxwell Pistilli, Lynn Cyert, T Rowan Candy, Graham Quinn and 1 more

Registry-linked trialOpen access · greenAbstract readMulticenter Study
In one paragraph

Article in Ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05538182 (Zimbabwe Eyecare And Learning), which is not on this map. Cited by 69 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 3 pooled it
19.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05538182 nacompletednot on this mapstarted 2022, after this paper: background citation

Zimbabwe Eyecare And Learning: Formative Research on Hyperopia and Educational Outcomes in Primary School Children in Mashonaland Central Province of Zimbabwe

TypeinterventionalSponsorQueen's University, BelfastRan2022 to 2023Enrolled1,883ConditionsHyperopia, Long SightArmsSpectacles
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 3 syntheses or guidelines pooled it, 130 citations in OpenAlex.

  1. Visual and Oculomotor Function in Developmental Dyslexia: A Systematic Review and Meta-Analysis.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Causes of Reduced Vision in Australian Children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Attention to text and pictures during storybook reading in preschool children with moderate hyperopia.Optometry and vision science : official publication of the American Academy of Optometry · 2026
    Article
  11. Impact of uncorrected hyperopia on visual function and academic performance in preschool and school-age children.Optometry and vision science : official publication of the American Academy of Optometry · 2026
    Review
  12. Article
  13. The QuickSee autorefractor reliably measures the accommodative response in children compared with the Shin-Nippon autorefractor.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  14. Review
  15. Recommended practices for vision screening in pre-school-age children: A 2025 update.Optometry and vision science : official publication of the American Academy of Optometry · 2025
    Review
  16. Article
  17. Article
  18. Evaluation of the QuickSee portable autorefractor system in a pediatric population.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2025
    Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

VIP-HIP Study Group
Marjean Taylor KulpThe Ohio State University, College of Optometry, Columbus, Ohio. Electronic address: Kulp.6@osu.edu.
Elise CinerPennsylvania College of Optometry at Salus University, Elkins Park, Pennsylvania.
Maureen MaguireDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania.
Bruce MooreNew England College of Optometry, Boston, Massachusetts.
Jill PentimontiAmerican Institutes for Research, Washington, DC.
Maxwell PistilliDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania.
Lynn CyertNortheastern State University College of Optometry, Tahlequah, Oklahoma.
T Rowan CandyIndiana University School of Optometry, Bloomington, Indiana.
Graham QuinnDivision of Ophthalmology, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
Gui-Shuang YingDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania.
University of Pennsylvania · USAmerican Institutes for Research · USChildren's Hospital of Philadelphia · USIndiana University Bloomington · USNew England College of Optometry · USNortheastern State University · USSalus University · USThe Ohio State University · US

Funding

Scientific TransparencyP30EY001583 · NEI · UNIVERSITY OF PENNSYLVANIA · PI Qi N Cui · 1985 to 2026
$19.5M
Vision In Preschoolers - Hyperopia in Children (VIP-HIP)R01EY021141 · NEI · OHIO STATE UNIVERSITY · PI CINER, ELISE B, KULP, MARJEAN T · 2011 to 2013
$2.6M
NEI NIH HHS P30 EY001583NEI NIH HHS R01 EY021141NEI NIH HHS R01EY021141
6 · The paper itself

Abstract

purposeTo compare early literacy of 4- and 5-year-old uncorrected hyperopic children with that of emmetropic children.

designCross-sectional.

participantsChildren attending preschool or kindergarten who had not previously worn refractive correction.

methodsCycloplegic refraction was used to identify hyperopia (≥3.0 to ≤6.0 diopters [D] in most hyperopic meridian of at least 1 eye, astigmatism ≤1.5 D, anisometropia ≤1.0 D) or emmetropia (hyperopia ≤1.0 D; astigmatism, anisometropia, and myopia <1.0 D). Threshold visual acuity (VA) and cover testing ruled out amblyopia or strabismus. Accommodative response, binocular near VA, and near stereoacuity were measured.

main outcome measuresTrained examiners administered the Test of Preschool Early Literacy (TOPEL), composed of Print Knowledge, Definitional Vocabulary, and Phonological Awareness subtests.

resultsA total of 492 children (244 hyperopes and 248 emmetropes) participated (mean age, 58 months; mean ± standard deviation of the most hyperopic meridian, +3.78±0.81 D in hyperopes and +0.51±0.48 D in emmetropes). After adjustment for age, race/ethnicity, and parent/caregiver's education, the mean difference between hyperopes and emmetropes was -4.3 (P = 0.01) for TOPEL overall, -2.4 (P = 0.007) for Print Knowledge, -1.6 (P = 0.07) for Definitional Vocabulary, and -0.3 (P = 0.39) for Phonological Awareness. Greater deficits in TOPEL scores were observed in hyperopic children with ≥4.0 D than in emmetropes (-6.8, P = 0.01 for total score; -4.0, P = 0.003 for Print Knowledge). The largest deficits in TOPEL scores were observed in hyperopic children with binocular near VA of 20/40 or worse (-8.5, P = 0.002 for total score; -4.5, P = 0.001 for Print Knowledge; -3.1, P = 0.04 for Definitional Vocabulary) or near stereoacuity of 240 seconds of arc or worse (-8.6, P < 0.001 for total score; -5.3, P < 0.001 for Print Knowledge) compared with emmetropic children.

conclusionsUncorrected hyperopia ≥4.0 D or hyperopia ≥3.0 to ≤6.0 D associated with reduced binocular near VA (20/40 or worse) or reduced near stereoacuity (240 seconds of arc or worse) in 4- and 5-year-old children enrolled in preschool or kindergarten is associated with significantly worse performance on a test of early literacy.

Indexed as

Accommodation, OcularChild, PreschoolCross-Sectional StudiesEducational MeasurementEducational StatusEmmetropiaFemaleHumansHyperopiaLiteracyMaleRefraction, OcularVision, BinocularVisual Acuity

Identifiers

PMID26826748
PMCPMC4808323
OpenAlexW2298775145

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.