Evidence map›Paper›PMID 26826159›Full record

SynthesisInternational journal of STD & AIDS2017

Prevalence of hepatitis C virus infection among HIV+ men who have sex with men: a systematic review and meta-analysis.

Ashly E Jordan, David C Perlman, Joshua Neurer, Daniel J Smith, Don C Des Jarlais, Holly Hagan

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of STD & AIDS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The hepatitis C epidemic in Canada: An overview of recent trends in surveillance, injection drug use, harm reduction and treatment.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021
    Article
  13. Review
  14. Observational
  15. Review
  16. Article
  17. Canadian results from the European Men-who-have-sex-with-men Internet survey (EMIS-2017).Canada communicable disease report = Releve des maladies transmissibles au Canada · 2019
    Article
  18. Article
  19. Article
  20. The seroprevalence of untreated chronic hepatitis C virus (HCV) infection and associated risk factors in male Irish prisoners: a cross-sectional study, 2017.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ashly E Jordan1 New York University, New York, NY, USA.
David C Perlman2 Center for Drug Use and HIV Research, New York, NY, USA.
Joshua Neurer1 New York University, New York, NY, USA.
Daniel J Smith1 New York University, New York, NY, USA.
Don C Des Jarlais2 Center for Drug Use and HIV Research, New York, NY, USA.
Holly Hagan1 New York University, New York, NY, USA.

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan, Courtney McKnight · 1998 to 2026
$38.9M
Substance Abuse Research Education and Training (SARET).R25DA022461 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOSHUA D LEE · 2007 to 2026
$6.5M
Addressing Hepatitis C and Hepatocellular Carcinoma: Current and Future EpidemicsR01DA034637 · NIDA · NEW YORK UNIVERSITY · PI HAGAN, HOLLY · 2013 to 2016
$2.5M
NIDA NIH HHS P30 DA011041NIDA NIH HHS R01 DA034637NIDA NIH HHS R25 DA022461
6 · The paper itself

Abstract

Since 2000, an increase in hepatitis C virus infection among HIV-infected (HIV+) men who have sex with men has been observed. Evidence points to blood exposure during sex as the medium of hepatitis C virus transmission. Hepatitis C virus prevalence among HIV + MSM overall and in relation to injection drug use is poorly characterized. In this study, a systematic review and meta-analysis examining global hepatitis C virus antibody prevalence and estimating active hepatitis C virus prevalence among HIV + MSM were conducted; 42 reports provided anti-hepatitis C virus prevalence data among HIV + MSM. Pooled prevalence produced an overall anti-hepatitis C virus prevalence among HIV + MSM of 8.1%; active HCV prevalence estimate was 5.3%-7.3%. Anti-hepatitis C virus prevalence among injection drug use and non-injection drug use HIV + MSM was 40.0% and 6.7%, respectively. Among HIV + MSM, hepatitis C virus prevalence increased significantly over time among the overall and non-injection drug use groups, and decreased significantly among injection drug use HIV + MSM. We identified a moderate prevalence of hepatitis C virus among all HIV + MSM and among non-injection drug use HIV + MSM; for both, prevalence was observed to be increasing slightly. Pooled prevalence of hepatitis C virus among HIV + MSM was higher than that observed in the 1945-1965 US birth cohort. The modest but rising hepatitis C virus prevalence among HIV + MSM suggests an opportunity to control HCV among HIV + MSM; this combined with data demonstrating a rising hepatitis C virus incidence highlights the temporal urgency to do so.

Indexed as

AdultCoinfectionHepatitis CHIV SeropositivityHomosexuality, MaleHumansMaleMiddle AgedPrevalenceSubstance Abuse, Intravenoushepatitis C virus infectionHIV/AIDSHIV/HCV co-infectionMen who have sex with menmeta-analysissystematic review

Identifiers

PMID26826159
PMCPMC4965334

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.