ArticleJournal of sleep research2016
Beta EEG reflects sensory processing in active wakefulness and homeostatic sleep drive in quiet wakefulness.
Article in Journal of sleep research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- The Caffeinated Brain Part 3: The Effect of Caffeine on Electroencephalography (EEG) During Wakefulness-A Systematic and Mechanistic Review.Nutrients · 2026Pooled it
- Functional changes in sleep-related arousal after ketamine administration in individuals with treatment-resistant depression.Translational psychiatry · 2024Trial
- SleepInvestigatoR: a flexible R function for analyzing scored sleep in rodents.Sleep advances : a journal of the Sleep Research Society · 2025Article
- Enhancing convolutional neural networks in electroencephalogram driver drowsiness detection using human inspired optimizers.Scientific reports · 2025Article
- CaScientific reports · 2025Article
- Open-Source Algorithm for Automated Vigilance State Classification Using Single-Channel Electroencephalogram in Rodents.Sensors (Basel, Switzerland) · 2025Article
- Transient cortical beta-frequency oscillations associated with contextual novelty in high density mouse EEG.Scientific reports · 2025Article
- Resting-State EEG Alterations of Practice-Related Spectral Activity and Connectivity Patterns in Depression.Biomedicines · 2024Article
- Purkinje cell dysfunction causes disrupted sleep in ataxic mice.Disease models & mechanisms · 2024Article
- Phase-Amplitude Coupling in Theta and Beta Bands: A Potential Electrophysiological Marker for Obstructive Sleep Apnea.Nature and science of sleep · 2024Article
- Article
- Effect of N-Acetylcysteine on Sleep: Impacts of Sex and Time of Day.Antioxidants (Basel, Switzerland) · 2023Article
- Probing pathways by which rhynchophylline modifies sleep using spatial transcriptomics.Biology direct · 2023Article
- Chronic dietary supplementation with nicotinamide riboside reduces sleep need in the laboratory mouse.Sleep advances : a journal of the Sleep Research Society · 2023Article
- Motivational and Valence-Related Modulation of Sleep/Wake Behavior are Mediated by Midbrain Dopamine and Uncoupled from the Homeostatic and Circadian Processes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Movement-related beta ERD and ERS abnormalities in neuropsychiatric disorders.Frontiers in neuroscience · 2022Review
- Adult Female Sleep During Hypoxic Bed Rest.Frontiers in neuroscience · 2022Article
- Article
- Frontal increase of beta modulation during the practice of a motor task is enhanced by visuomotor learning.Scientific reports · 2021Article
- Diurnal changes in perineuronal nets and parvalbumin neurons in the rat medial prefrontal cortex.Brain structure & function · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Markers of sleep drive (<10 Hz; slow-wave activity and theta) have been identified in the course of slow-wave sleep and wakefulness. So far, higher frequencies in the waking electroencephalogram have not been examined thoroughly as a function of sleep drive. Here, electroencephalogram dynamics were measured in epochs of active wake (wake characterized by high muscle tone) or quiet wake (wake characterized by low muscle tone). It was hypothesized that the higher beta oscillations (15-35 Hz, measured by local field potential and electroencephalography) represent fundamentally different processes in active wake and quiet wake. In active wake, sensory stimulation elevated beta activity in parallel with gamma (80-90 Hz) activity, indicative of cognitive processing. In quiet wake, beta activity paralleled slow-wave activity (1-4 Hz) and theta (5-8 Hz) in tracking sleep need. Cerebral lactate concentration, a measure of cerebral glucose utilization, increased during active wake whereas it declined during quiet wake. Mathematical modelling of state-dependent dynamics of cortical lactate concentration was more precisely predictive when quiet wake and active wake were included as two distinct substates rather than a uniform state of wakefulness. The extent to which lactate concentration declined in quiet wake and increased in active wake was proportionate to the amount of beta activity. These data distinguish quiet wake from active wake. Quiet wake, particularly when characterized by beta activity, is permissive to metabolic and electrophysiological changes that occur in slow-wave sleep. These data urge further studies on state-dependent beta oscillations across species.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.